Findings

What do systematic reviews say?

46 questions · 46 findings · 15 reviews · Pain, Palliative and Supportive Care

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No studies found 6 · 13%GRADE not reported 0 · 0%Very low 12 · 26.1%Low 15 · 32.6%Moderate 10 · 21.7%High 3 · 6.5%

Dexketoprofen 10 mg‐12.5 mg vs placebo

Number of women requiring rescue medication · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 373 participants
High

Dexketoprofen 20 mg or 25 mg vs placebo

Median (mean) time to use of rescue medication · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 281 participants
Very low

Dexketoprofen 20 mg or 25 mg vs placebo

Number of women requiring rescue medication · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 445 participants
High

Ketoprofen 25 mg vs placebo

Median (mean) time to use of rescue medication · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 188 participants
Very low

Ketoprofen 25 mg vs placebo

Number of women requiring rescue medication · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 402 participants
Moderate

Ketoprofen 50 mg vs placebo

Median (mean) time to use of rescue medication · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 77 participants
Very low

Ketoprofen 50 mg vs placebo

Number of women requiring rescue medication · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 263 participants
High

Aspirin 1000 mg vs placebo

Use of rescue medication · adults with episodic tension‐type headache

1 finding from 1 review

Aspirin for acute treatment of episodic tension‐type headache in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 397 participants
Low

TENS vs sham TENS

Analgesic (painkiller) use · adults with neuropathic pain

The review found no eligible studies for this question.

1 finding from 1 review

Transcutaneous electrical nerve stimulation (TENS) for neuropathic pain in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Paracetamol 500 mg to 650 mg vs placebo

Use of rescue medication · adults with episodic tension‐type headache

1 finding from 1 review

Paracetamol (acetaminophen) for acute treatment of episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Paracetamol 1000 mg vs placebo

Use of rescue medication · adults with episodic tension‐type headache

1 finding from 1 review

Paracetamol (acetaminophen) for acute treatment of episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Ketoprofen 25 mg vs placebo

Use of rescue medication · adults with episodic tension‐type headache

1 finding from 1 review

Ketoprofen for episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Dexketoprofen 25 mg plus tramadol 75 mg vs placebo

Median (mean) time to use of rescue medication · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single fixed‐dose oral dexketoprofen plus tramadol for acute postoperative pain in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 62 participants
Moderate

Dexketoprofen 25 mg plus tramadol 75 mg vs placebo

Number of women requiring rescue medication · adults with moderate or severe acute postoperative pain

1 finding from 1 review

Single fixed‐dose oral dexketoprofen plus tramadol for acute postoperative pain in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 123 participants
Very low

SSRIs or SNRIs vs amitriptyline

Symptomatic/analgesic medication use for acute headache attacks · patients for whom migraine preventive interventions are indicated

The review found no eligible studies for this question.

1 finding from 1 review

Selective serotonin reuptake inhibitors (SSRIs) and serotonin‐norepinephrine reuptake inhibitors (SNRIs) for the… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

SSRIs or SNRIs vs placebo

Symptomatic/analgesic medication use for acute headache attacks · patients for whom migraine preventive interventions are indicated

1 finding from 1 review

Selective serotonin reuptake inhibitors (SSRIs) and serotonin‐norepinephrine reuptake inhibitors (SNRIs) for the… 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 113 participants
Low

Intervention not reported

Use of rescue medication over 6 hours · Adults with episodic tension‐type headache

1 finding from 1 review

Ibuprofen for acute treatment of episodic tension‐type headache in adults 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 589 participants
Low

SSRIs or SNRIs vs other antidepressants

Symptomatic/analgesic medication use for acute headache attacks · patients with tension‐type headache

1 finding from 1 review

Selective serotonin reuptake inhibitors (SSRIs) and serotonin‐norepinephrine reuptake inhibitors (SNRIs) for the… 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 152 participants
Low

SSRIs or SNRIs vs placebo

Symptomatic/analgesic medication use for acute headache attacks · patients with tension‐type headache

1 finding from 1 review

Selective serotonin reuptake inhibitors (SSRIs) and serotonin‐norepinephrine reuptake inhibitors (SNRIs) for the… 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 118 participants
Low

Cannabis‐based medicines vs placebo medication

Proportion of participants reporting no worse than mild pain by 14 days after start of treatment · adults with cancer‐related pain

The review found no eligible studies for this question.

1 finding from 1 review

Cannabis‐based medicines and medical cannabis for adults with cancer pain 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found