Cochrane · systematic review · CD012232
Single fixed‐dose oral dexketoprofen plus tramadol for acute postoperative pain in adults
Derry, S, Cooper, TE, Phillips, T · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
Pain, Palliative and Supportive CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 60%Low 0 · 0%Moderate 2 · 40%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Dexketoprofen 25 mg plus tramadol 75 mg compared with placebo for acute postoperative pain
Population: adults with moderate or severe acute postoperative pain
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Participants with ≥ 50% pain relief over 6 hours Dexketoprofen 25 mg plus tramadol 75 mg vs placebo | no estimate extracted | 3 studies · 748 participants | Moderate |
Median time to use of rescue medication Dexketoprofen 25 mg plus tramadol 75 mg vs placebo | no estimate extracted | 1 study · 62 participants | Moderate |
Participants using rescue medication over 6 hours Dexketoprofen 25 mg plus tramadol 75 mg vs placebo | no estimate extracted | 1 study · 123 participants | Very low |
Participants with ≥ 1 adverse event following a single dose, and after 3 to 5 days Dexketoprofen 25 mg plus tramadol 75 mg vs placebo | no estimate extracted | 1 study · 123 participants | Very low |
Participants with a serious adverse event following a single dose, and after 3 to 5 days Dexketoprofen 25 mg plus tramadol 75 mg vs placebo | no estimate extracted | 1 study · 123 participants | Very low |