Question · asked by 1 review

SSRIs or SNRIs vs placebo: Symptomatic/analgesic medication use for acute headache attacks

Population
patients for whom migraine preventive interventions are indicated
Intervention
SSRIs or SNRIs
Comparison
placebo
Outcome
Symptomatic/analgesic medication use for acute headache attacks

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
SSRIs or SNRIs vs placebo
Symptomatic/analgesic medication use for acute headache attacks · patients for whom migraine preventive interventions are indicated
Selective serotonin reuptake inhibitors (SSRIs) and serotonin‐norepinephrine reuptake inhibitors (SNRIs) for… (2015) · Cochrane Headline outcomes only
no estimate extracted2 studies · 113 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Selective serotonin reuptake inhibitors (SSRIs) and serotonin‐norepinephrine reuptake inhibitors (SNRIs) for the prevention of migraine in…
2015 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.