Findings

What do systematic reviews say?

55 questions · 57 findings · 15 reviews · Neonatal

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No studies found 17 · 29.8%GRADE not reported 0 · 0%Very low 12 · 21.1%Low 21 · 36.8%Moderate 7 · 12.3%High 0 · 0%

Lateral decubitus position vs prone position

Episodes of bradycardia · lumbar puncture in newborn infants

The review found no eligible studies for this question.

1 finding from 1 review

Positioning for lumbar puncture in newborn infants 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

High MCT formula vs low MCT formula

Long‐term growth outcomes · promoting short‐term growth of preterm infants

The review found no eligible studies for this question.

1 finding from 1 review

High versus low medium chain triglyceride content of formula for promoting short‐term growth of preterm infants 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Supine midline head position vs any other supine head position

Long‐term neurodevelopmental outcome ‒not reported · very preterm infants with or at risk of germinal matrix‐intraventricular haemorrhage in preterm infants

The review found no eligible studies for this question.

1 finding from 1 review

Head midline position for preventing the occurrence or extension of germinal matrix‐intraventricular haemorrhage in… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Feed thickener vs control

Duration of longest reflux episode · Formula‐fed healthy term infants up to 6 months of age with gastro‐oesophageal reflux

1 finding from 1 review

Feed thickener for infants up to six months of age with gastro‐oesophageal reflux 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 116 participants
Low

Prone vs lateral

Long‐term complications (neurodevelopmental) · neonates with mechanical ventilation

The review found no eligible studies for this question.

1 finding from 1 review

Infant position in neonates receiving mechanical ventilation 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prone vs lateral

Long‐term complications (bronchopulmonary dysplasia, chronic lung disease) · neonates with mechanical ventilation

The review found no eligible studies for this question.

1 finding from 1 review

Infant position in neonates receiving mechanical ventilation 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prone vs supine

Long‐term complications (neurodevelopmental) · neonates with mechanical ventilation

The review found no eligible studies for this question.

1 finding from 1 review

Infant position in neonates receiving mechanical ventilation 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Lateral vs supine

Long‐term complications (neurodevelopmental) · neonates with mechanical ventilation

The review found no eligible studies for this question.

1 finding from 1 review

Infant position in neonates receiving mechanical ventilation 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Lateral vs supine

Long‐term complications (bronchopulmonary dysplasia, chronic lung disease) · neonates with mechanical ventilation

The review found no eligible studies for this question.

1 finding from 1 review

Infant position in neonates receiving mechanical ventilation 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prone vs supine

Long‐term complications (bronchopulmonary dysplasia, chronic lung disease) · neonates with mechanical ventilation

The review found no eligible studies for this question.

1 finding from 1 review

Infant position in neonates receiving mechanical ventilation 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

All‐cause mortality: longest · infants 1 to 6 months of age

The intervention showed no clear difference in all‐cause mortality: longest (moderate certainty).

1 finding from 1 review

Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age 2016 · Cochrane Headline outcomes only
RR 1.05 [0.89, 1.25]
9 studies · 21339 participants
Moderate

Rescue high‐frequency jet ventilation vs conventional ventilation

Neurodevelopmental outcomes · preterm infants with severe pulmonary dysfunction

The review found no eligible studies for this question.

1 finding from 1 review

Rescue high‐frequency jet ventilation versus conventional ventilation for severe pulmonary dysfunction in preterm… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Short feeding interval vs long feeding interval

Days taken to achieve full feeding · preterm infants less than 1500 grams

1 finding from 1 review

Short versus long feeding interval for bolus feedings in very preterm infants 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 351 participants
Low

Short feeding interval vs long feeding interval

Days to regain birth weight · preterm infants less than 1500 grams

1 finding from 1 review

Short versus long feeding interval for bolus feedings in very preterm infants 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 350 participants
Low

Short feeding interval vs long feeding interval

Length of hospital stay · preterm infants less than 1500 grams

1 finding from 1 review

Short versus long feeding interval for bolus feedings in very preterm infants 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 207 participants
Very low

Short feeding interval vs long feeding interval

Necrotising enterocolitis · preterm infants less than 1500 grams

Short feeding interval showed no clear difference in necrotising enterocolitis compared with long feeding interval (low certainty).

1 finding from 1 review

Short versus long feeding interval for bolus feedings in very preterm infants 2021 · Cochrane Headline outcomes only
RR 1.07 [0.54, 2.11]
4 studies · 417 participants
Low

Short feeding interval vs long feeding interval

Rate of weight gain (g/kg/day) · preterm infants less than 1500 grams

The review found no eligible studies for this question.

1 finding from 1 review

Short versus long feeding interval for bolus feedings in very preterm infants 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

LCPUFA supplemented formula vs control formula

Visual acuity · term infants

LCPUFA supplemented formula showed no clear difference in visual acuity/Teller cards at 12 months (cycles/degree) ‐ DHA and AA… compared with control formula (low certainty).

1 finding from 1 review

Long chain polyunsaturated fatty acid supplementation in infants born at term 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 256 participants
Low

LCPUFA supplemented formula vs control formula

Sweep VEP acuity at 12 months (LogMAR) ‐ DHA and AA vs normal term formula · term infants

LCPUFA supplemented formula showed no clear difference in sweep VEP acuity at 12 months (LogMAR) ‐ DHA and AA vs normal term… compared with control formula (low certainty).

1 finding from 1 review

Long chain polyunsaturated fatty acid supplementation in infants born at term 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 244 participants
Low

LCPUFA supplemented formula vs control formula

MDI scores (Bayley) at 18 months ‐ DHA and AA vs normal term formula · term infants

LCPUFA supplemented formula showed no clear difference in MDI scores (Bayley) at 18 months ‐ DHA and AA vs normal term formula compared with control formula (low certainty).

1 finding from 1 review

Long chain polyunsaturated fatty acid supplementation in infants born at term 2017 · Cochrane Headline outcomes only
MD 0.06
4 studies · 661 participants
Low