Cochrane · systematic review · CD003668
Infant position in neonates receiving mechanical ventilation
Rivas‐Fernandez, M, Roqué i Figuls, M, Diez‐Izquierdo, A, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
27
current version
GRADE rated
6
No studies
21
Included studies
NR
No studies 21 · 77.8%Ungraded 0 · 0%Very low 3 · 11.1%Low 1 · 3.7%Moderate 2 · 7.4%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Prone compared with supine for newborn ventilated
Population: neonates with mechanical ventilation
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death (neonatal or infant) ‐ not reported Prone vs supine | no estimate extracted | NR | No studies |
Long‐term complications (neurodevelopmental) Prone vs supine | no estimate extracted | NR | No studies |
Long‐term complications (bronchopulmonary dysplasia, chronic lung disease) Prone vs supine | no estimate extracted | NR | No studies |
Short‐term complications (respiratory) Prone vs supine | no estimate extracted | NR | No studies |
Short‐term complications (procedural) Prone vs supine | no estimate extracted | NR | No studies |
Periventricular or intraventricular haemorrhage Prone vs supine | no estimate extracted | NR | No studies |
Oxygenation: PO2 (mmHg)a Prone vs supine | no estimate extracted | 3 studies · 116 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Oxygenation: SpO2e Prone vs supine | no estimate extracted | 9 studies · 308 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
SpO2 at ‐ sensitivity low risk; selection bias Prone vs supine | no estimate extracted | 4 studies · 92 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Desaturations Prone vs supine | no estimate extracted | 3 studies · 178 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Prone compared with lateral for neonates with mechanical ventilation
Population: neonates with mechanical ventilation
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death (neonatal or infant) Prone vs lateral | no estimate extracted | NR | No studies |
Long‐term complications (neurodevelopmental) Prone vs lateral | no estimate extracted | NR | No studies |
Long‐term complications (bronchopulmonary dysplasia, chronic lung disease) Prone vs lateral | no estimate extracted | NR | No studies |
Short‐term complications (respiratory) Prone vs lateral | no estimate extracted | NR | No studies |
Short‐term complications (procedural) Prone vs lateral | no estimate extracted | NR | No studies |
Periventricular or intraventricular haemorrhage Prone vs lateral | no estimate extracted | NR | No studies |
Oxygenation SpO2a Prone vs lateral | no estimate extracted | 5 studies · 206 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Desaturations Prone vs lateral | no estimate extracted | NR | No studies |
Lateral compared with supine for neonates with mechanical ventilation
Population: neonates with mechanical ventilation
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death (neonatal or infant) Lateral vs supine | no estimate extracted | NR | No studies |
Long‐term complications (neurodevelopmental) Lateral vs supine | no estimate extracted | NR | No studies |
Long‐term complications (bronchopulmonary dysplasia, chronic lung disease) Lateral vs supine | no estimate extracted | NR | No studies |
Short‐term complications (respiratory) Lateral vs supine | no estimate extracted | NR | No studies |
Short‐term complications (procedural) Lateral vs supine | no estimate extracted | NR | No studies |
Periventricular or intraventricular haemorrhage Lateral vs supine | no estimate extracted | NR | No studies |
Bronchopulmonary dysplasia or chronic lung disease Lateral vs supine | no estimate extracted | NR | No studies |
Oxygenation SpO21 Lateral vs supine | no estimate extracted | 5 studies · 206 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Desaturations Lateral vs supine | no estimate extracted | NR | No studies |