Cochrane · systematic review · CD000376

Long chain polyunsaturated fatty acid supplementation in infants born at term

Jasani, B, Simmer, K, Patole, SK, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 7 · 100%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

LCPUFA supplemented formula compared with control formula for term infants

Population: term infants
7 questions
OutcomeEffectEvidenceStatus / GRADE
Visual acuity/Teller cards at 12 months (cycles/degree) ‐ DHA and AA vs normal term formula
LCPUFA supplemented formula vs control formula
no estimate extracted3 studies · 256 participantsLow
Sweep VEP acuity at 12 months (LogMAR) ‐ DHA and AA vs normal term formula
LCPUFA supplemented formula vs control formula
no estimate extracted3 studies · 244 participantsLow
MDI scores (Bayley) at 18 months ‐ DHA and AA vs normal term formula
LCPUFA supplemented formula vs control formula
MD 0.064 studies · 661 participantsLow
PDI scores (Bayley) at 18 months ‐ DHA and AA vs normal term formula
LCPUFA supplemented formula vs control formula
MD 0.694 studies · 661 participantsLow
Weight at 12 months (z scores) ‐ DHA and AA vs normal term formula
LCPUFA supplemented formula vs control formula
no estimate extracted5 studies · 521 participantsLow
Length at 12 months (z scores) ‐ DHA and AA vs normal term formula
LCPUFA supplemented formula vs control formula
no estimate extracted5 studies · 521 participantsLow
Head circumference at 12 months (z scores) ‐ DHA and AA vs normal term formula
LCPUFA supplemented formula vs control formula
no estimate extracted4 studies · 464 participantsLow