Dental caries · Individuals in Ethiopia assessed for dental caries
Sweet food consumption was associated with significantly higher odds of dental caries (OR 2.4, 95% CI 1.91 to 3.01); certainty not graded.
1 finding from 1 review
Water samples with fluoride concentration above the acceptable range · Brazilian cities in the Northeast region with artificially fluoridated public water supplies
In the Northeast region, 0.2% of samples were above the acceptable range.
1 finding from 1 review
Prevalence 0.2
Studies not reported
GRADE not reported
Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies
In prospective cohorts, adults with 1-19 teeth had a higher cumulative incidence of ACVD-related events than adults with 20-32 teeth (RR 1.69, 95% CI 1.13 to 2.53; 2 cohort studies, I2=60%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
1 finding from 1 review
Intervention not reported
Initiation of white spot lesions (WSL), visual-tactile assessment
The intervention showed no clear difference in initiation of white spot lesions (WSL), visual-tactile assessment; GRADE not reported.
1 finding from 1 review
RR 0.82 [0.66, 1.02]
Studies not reported
GRADE not reported
Intervention not reported
Initiation of white spot lesions (WSL), visual-tactile assessment
The intervention showed no clear difference in initiation of white spot lesions (WSL), visual-tactile assessment; GRADE not reported.
1 finding from 1 review
RR 0.85 [0.66, 1.10]
Studies not reported
GRADE not reported
Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
For resin-based sealants, fluoride release did not significantly change WSL initiation (RR 0.71, wide CI); subgroup not separately GRADE-rated.
1 finding from 1 review
DMFT/DMFS index (dental caries experience) · Adults (general and hospital populations assessed in case-control studies)
No statistically significant difference in DMFT index between SSc patients and controls (SMD -0.03, CI includes 0); certainty ungraded.
1 finding from 1 review
Dental caries in children · Children in cross-sectional studies from Asia
Maternal smoking during pregnancy was associated with higher odds of childhood caries in the Asia subgroup.
1 finding from 1 review
OR 1.84 [1.39, 2.45]
2 studies
GRADE not reported
Iron deficiency (as defined by trialists) · Preschool children (<6 years)
In a sensitivity analysis excluding one outlier study, ECC remained associated with higher odds of iron deficiency (OR 2.76, 95% CI 2.42 to 3.13); ungraded.
2 findings from 1 review
Intervention not reported
Dental caries prevalence · General population (children and adults) in East Africa
Caries prevalence in primary dentition was 39.5% (95% CI 26.9 to 52.1); certainty not graded.
1 finding from 1 review
Full-mouth bleeding score (FMBS) · Adolescents/teenagers undergoing orthodontic treatment
A single study reported a lower full-mouth bleeding score with aligners versus fixed appliances in adolescents at 12 months (MD -20.44, 95% CI -22.98 to -17.90; ungraded).
1 finding from 1 review
Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
The additional use of a sealant probably reduces the initiation of white spot lesions during fixed orthodontic treatment compared with no sealant (RR 0.70), but the certainty of evidence is very low.
1 finding from 1 review
Iron deficiency anaemia · Preschool children (<6 years)
Children with early childhood caries were more likely to have iron-deficiency anemia than caries-free children (OR 2.74, 95% CI 2.41 to 3.11); ungraded.
1 finding from 1 review
Maximal mouth opening (interincisal distance) · Adults (general and hospital populations assessed in case-control studies)
Systemic sclerosis patients have significantly reduced mouth opening compared with controls (SMD -1.06); certainty ungraded.
1 finding from 1 review
Serum ferritin (ng/mL) · Preschool children (<6 years)
Serum ferritin levels did not differ significantly between children with ECC and caries-free children (mean difference -5.80, 95% CI -11.97 to 0.37); ungraded.
1 finding from 1 review
White spot lesions assessed by laser fluorescence (DIAGNOdent) · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
White spot lesions were also measured by laser fluorescence in 3 fluoride-vs-non-fluoride studies, but no meta-analysis was possible due to incompatible reporting.
1 finding from 1 review
Dental caries · Individuals in East Africa assessed for dental caries
Frequent carbohydrate intake was associated with significantly higher odds of dental caries (OR 1.575, 95% CI 1.13 to 3.051); certainty not graded.
1 finding from 1 review
Number of teeth · Adults (general and hospital populations assessed in case-control studies)
No statistically significant difference in number of teeth between SSc patients and controls (SMD -0.95, CI includes 0); certainty ungraded.
1 finding from 1 review
Intervention not reported
Dental caries prevalence · General population (children and adults) in East Africa
Caries prevalence in mixed dentition (6-12 years) was 41.3% (95% CI 33.5 to 49.2); certainty not graded.
1 finding from 1 review
Intervention not reported
Mean DMFT (decayed, missing, filled permanent teeth) · Individuals with permanent dentition in East Africa
The pooled mean DMFT (permanent dentition) in East Africa was 1.941 (95% CI 1.561 to 2.322); certainty not graded.
1 finding from 1 review