Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,615 questions · 1,673 findings · 190 reviews · Headline outcomes only

No studies found 278 · 16.6%GRADE not reported 85 · 5.1%Very low 328 · 19.6%Low 460 · 27.5%Moderate 402 · 24%High 120 · 7.2%

Summary of findings: Trihexyphenidyl vs placebo

Participation in activities of daily living:individual goal setting Measured by: GAS (up to 5 functional goals scored on a 5‐point scale (−2 = much less than expected to +2 = much more than expected); higher score = better than expected outcome) · children with dystonic cerebral palsy
1 finding from 1 review

Summary of findings: Trihexyphenidyl vs placebo

Participation in activities of daily living:satisfaction with individual goals Measured by: satisfaction subscale of the COPM (satisfaction with performance in up to 5 problem areas scored on a 10‐point scale (1 = not satisfied at all to 10 = extr... · children with dystonic cerebral palsy
1 finding from 1 review

Summary of findings: Trihexyphenidyl vs placebo

Participation in activities of daily living:performance of individual goals Measured by: performance subscale of the COPM (up to five problem areas scored on a 10‐point scale (1 = not able to do to 10 = able to do extremely well; higher score = be... · children with dystonic cerebral palsy
1 finding from 1 review

Group‐format behavioural programmes vs alternative support

Group programme compared to face‐to‐face individual intervention · people who smoke

Group‐format behavioural programmes showed no clear difference in group programme compared to face‐to‐face individual intervention compared with alternative support (moderate certainty).

1 finding from 1 review

Intervention not reported

Residual pleural fluid on chest X‐ray at 8 weeks · adults and adolescents with pleural TB

The intervention may leads to lower residual pleural fluid on chest X‐ray at 8 weeks (low certainty).

1 finding from 1 review

Intervention not reported

Residual pleural fluid on chest X‐ray at 24 weeks · adults and adolescents with pleural TB

The intervention may leads to lower residual pleural fluid on chest X‐ray at 24 weeks (low certainty).

1 finding from 1 review

Intervention not reported

Global state: No clinically important overall improvement (as rated by individual trials) ‐ medium term ( · People with schizophrenia and schizophrenia‐like disorders

The intervention may leads to lower global state: No clinically important overall improvement (as rated… (low certainty).

1 finding from 1 review