Cochrane · systematic review · CD001876

Corticosteroids for tuberculous pleurisy

Ryan, H, Yoo, J, Darsini, P · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

Infectious DiseasesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 42.9%Low 4 · 57.1%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Comparison

Population: adults and adolescents with pleural TB
7 questions
OutcomeEffectEvidenceStatus / GRADE
Residual pleural fluid on chest X‐ray at 8 weeks
RR 0.54 [0.37, 0.78]2 studies · 237 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Residual pleural fluid on chest X‐ray at 24 weeks
RR 0.35 [0.18, 0.66]2 studies · 237 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Pleural changes at the end of
RR 0.72 [0.57, 0.92]5 studies · 393 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Long‐term functional respiratory impairment (> 6 months)
no estimate extracted2 studies · 187 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Adverse events leading to treatment discontinuation (
RR 2.78 [1.11, 6.94]6 studies · 590 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
HIV‐related infections (cryptococcal meningitis)
RR 0.59 [0.15, 2.42]1 study · 103 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
HIV‐related cancer (Kaposi's sarcoma)
RR 12.87 [0.73, 225.4]1 study · 103 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness