evidencegaps
Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

1,271 questions · 1,326 findings · 329 reviews

Sort:Best matchNewestHighest certaintyDownload CSV
No studies found 247 · 18.6%GRADE not reported 237 · 17.9%Very low 379 · 28.6%Low 285 · 21.5%Moderate 141 · 10.6%High 37 · 2.8%

Cemented vs uncemented hemiarthroplasty

Mobility, early (within 4 months): able to walk outdoors using no more than 1 walking aid. · adults with displaced and undisplaced hip fractures

Cemented showed no clear difference in mobility, early (within 4 months): able to walk outdoors using no… compared with uncemented hemiarthroplasty (moderate certainty).

1 finding from 1 review

Vitrectomy vs vitreous tap biopsy and antibiotic injection

Improvement in visual acuity at 3 months' · people with endophthalmitis following intraocular surgery

It is very uncertain whether vitrectomy changes proportion of people with a visual acuity improvement of 10 letters… compared with vitreous tap biopsy and antibiotic injection (very low certainty).

1 finding from 1 review

Phacoemulsification vs laser peripheral iridotomy

Progression of visual field loss (worsening of one or more stages, accordingto the Glaucoma Staging System‐2) (at 12 months) · participants with primary angle‐closure glaucoma

Phacoemulsification probably leads to lower progression of visual field loss (worsening of one or more stages,… compared with laser peripheral iridotomy (moderate certainty).

1 finding from 1 review

Antibiotics vs placebo compared

Treatment failure (development of more severe signs and symptoms by the end of treatment) · children, aged 2 to 59 months, with WHO‐defined non‐severe pneumonia and wheeze

Antibiotic therapy may leads to lower treatment failure (development of more severe signs and symptoms by… compared with placebo compared to placebo (low certainty).

1 finding from 1 review

Belimumab 10 mg/kg vs placebo

Participants with one or more serious adverse events · people with active systemic lupus erythematosus (but not active nephritis or active central nervous system involvement)

Belimumab 10 mg/kg showed no clear difference in participants with one or more serious adverse events compared with placebo (low certainty).

1 finding from 1 review

Belimumab 10 mg/kg vs placebo

Participants with one or more serious infections · people with active systemic lupus erythematosus (but not active nephritis or active central nervous system involvement)

Belimumab 10 mg/kg showed no clear difference in participants with one or more serious infections compared with placebo (moderate certainty).

1 finding from 1 review

Levetiracetam vs phenobarbital

50% or greater reduction in seizure frequency · patients with AD and epileptic seizures

It is very uncertain whether levetiracetam changes reduction in seizure frequency of 50% or more compared with phenobarbital (very low certainty).

1 finding from 1 review

Lamotrigine vs phenobarbital

50% or greater reduction in seizure frequency · patients with AD and epileptic seizures

It is very uncertain whether lamotrigine changes reduction in seizure frequency of 50% or more compared with phenobarbital (very low certainty).

1 finding from 1 review

Levetiracetam vs lamotrigine

50% or greater reduction in seizure frequency · patients with AD and epileptic seizures

It is very uncertain whether levetiracetam changes reduction in seizure frequency of 50% or more compared with lamotrigine (very low certainty).

1 finding from 1 review