Findings

What do systematic reviews say?

3,454 questions · 3,562 findings · 816 reviews · Headline outcomes only

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No studies found 538 · 15.1%GRADE not reported 239 · 6.7%Very low 933 · 26.2%Low 1,041 · 29.2%Moderate 612 · 17.2%High 199 · 5.6%

Decompressive surgery plus radiotherapy vs radiotherapy

Survival (short term) At 30 days · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…

Decompressive surgery plus radiotherapy showed no clear difference in survival (short term) At 30 days compared with radiotherapy (low certainty).

1 finding from 1 review

Interventions for the treatment of metastatic extradural spinal cord compression in adults 2015 · Cochrane Headline outcomes only
RR 1.09 [0.96, 1.24]
1 study · 101 participants
Low

Normal saline plus standard treatment vs usual care

Mean days to wellness Patient reports · patients with acute upper respiratory tract infections

1 finding from 1 review

Saline nasal irrigation for acute upper respiratory tract infections 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 111 participants
Very low

Workplace interventions vs usual care

Sickness absence days, medium‐term · workers on sick leave

1 finding from 1 review

Workplace interventions to prevent work disability in workers on sick leave 2015 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1164 participants
High

Preoperative vessel imaging by ultrasound mapping vs standard preoperative care

Rate of interventions required to maintain patency (per 1000 patient‐days) · people with ESRD receiving haemodialysis through an arteriovenous fistula

1 finding from 1 review

Preoperative vascular access evaluation for haemodialysis patients 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 70 participants
Very low

Early vs late tracheostomy

Ventilator‐free days up to day 28 · critically ill patients

1 finding from 1 review

Early versus late tracheostomy for critically ill patients 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 335 participants
Moderate

Early vs late tracheostomy

Days of MV during 1 to 60 days · critically ill patients

1 finding from 1 review

Early versus late tracheostomy for critically ill patients 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 336 participants
Very low

Early vs late tracheostomy

ICU discharge (at day 28 after randomization) · critically ill patients

Early leads to higher ICU discharge (at day 28 after randomization) compared with late tracheostomy (high certainty).

1 finding from 1 review

Early versus late tracheostomy for critically ill patients 2015 · Cochrane Headline outcomes only
RR 1.29 [1.08, 1.55]
2 studies · 538 participants
High

Paroxetine vs placebo

Frequency of use % of heavy drinking days at the end of treatment · people with anxiety and comorbid alcohol use disorders

1 finding from 1 review

Pharmacotherapy for anxiety and comorbid alcohol use disorders 2015 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Paroxetine vs placebo

Percent of days abstinent · people with anxiety and comorbid alcohol use disorders

1 finding from 1 review

Pharmacotherapy for anxiety and comorbid alcohol use disorders 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 54 participants
Very low

Paroxetine vs placebo

Drinks per drinking day · people with anxiety and comorbid alcohol use disorders

1 finding from 1 review

Pharmacotherapy for anxiety and comorbid alcohol use disorders 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 54 participants
Very low

Antibiotics (short duration) vs prolonged‐course antibiotic therapy be used

28‐day antibiotic‐free days · hospital‐acquired pneumonia

1 finding from 1 review

Short‐course versus prolonged‐course antibiotic therapy for hospital‐acquired pneumonia in critically ill adults 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 431 participants
Low

Fresh frozen plasma vs no plasma

Short‐term mortality (up to 30 days) · Neonates, children and adults undergoing cardiovascular surgery

1 finding from 1 review

Fresh frozen plasma for cardiovascular surgery 2015 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 287 participants
Very low

Chronic disease management vs usual care

Days off work · adults with asthma

The review found no eligible studies for this question.

1 finding from 1 review

Chronic disease management programmes for adults with asthma 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Milnacipran 100 mg/day · adults with fibromyalgia

1 finding from 1 review

Milnacipran for pain in fibromyalgia in adults 2015 · Cochrane Headline outcomes only
no estimate extracted
100 participants
GRADE not reported

Intervention not reported

Milnacipran 200 mg/day · adults with fibromyalgia

1 finding from 1 review

Milnacipran for pain in fibromyalgia in adults 2015 · Cochrane Headline outcomes only
no estimate extracted
200 participants
GRADE not reported

Positive pressure therapy vs placebo

Proportion of days with vertigo in 4 weeks: vertigo scores > 2 · Ménière’s disease

1 finding from 1 review

Positive pressure therapy for Ménière's disease or syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 62 participants
Moderate

Positive pressure therapy vs placebo

Vertigo days in 4 months: vertigo scores > 2 · Ménière’s disease

1 finding from 1 review

Positive pressure therapy for Ménière's disease or syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 68 participants
Moderate

Positive pressure therapy vs placebo

Days of sick‐leave at 1 year · Ménière’s disease

1 finding from 1 review

Positive pressure therapy for Ménière's disease or syndrome 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 125 participants
Moderate

Any growth factor vs placebo or no growth factor

Ulcer‐free days following treatment for diabetic foot ulcers (free from any recurrence) · people with diabetes and foot ulcers

1 finding from 1 review

Growth factors for treating diabetic foot ulcers 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 55 participants
GRADE not reported

Lidocaine vs disopyramide

Overall survival at 30 days after myocardial infarction · patients with myocardial infarction

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic lidocaine for myocardial infarction 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found