Cochrane · systematic review · CD006821
Saline nasal irrigation for acute upper respiratory tract infections
King, D, Mitchell, B, Williams, CP, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
Acute Respiratory InfectionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 66.7%Low 1 · 33.3%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Normal saline plus standard treatment compared to standard treatment alone for acute upper respiratory tract infections
Population: patients with acute upper respiratory tract infections
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mean days to wellness Patient reports Normal saline plus standard treatment vs standard treatment alone | no estimate extracted | 2 studies · 111 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Antibiotic usage Patient‐reported usage Normal saline plus standard treatment vs standard treatment alone | OR 0.65 [0.29, 1.46] | 2 studies · 422 participants | Very low Downgraded: risk of bias, imprecision |
Sore throat Patient‐reported symptoms Scale from: 1 to 4 Normal saline plus standard treatment vs standard treatment alone | no estimate extracted | 1 study · 390 participants | Low Downgraded: risk of bias |