Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

393 questions · 411 findings · 111 reviews

No studies found 51 · 12.4%GRADE not reported 40 · 9.7%Very low 86 · 20.9%Low 121 · 29.4%Moderate 84 · 20.4%High 29 · 7.1%

ProSeal vs Classic laryngeal mask airway (LMA)

Inadequate oxygenation (SaO₂ < 90% on peripheral oxygen saturation) · adult patients (18 years of age and older) for positive pressure ventilation undergoing elective surgery

It is very uncertain whether proSeal changes inadequate oxygenation (SaO₂ < 90% on peripheral oxygen saturation) compared with classic laryngeal mask airway (LMA) (very low certainty).

1 finding from 1 review

Cerebral NIRS oximetry vs no cerebral NIRS oximetry

Oxygen requirement at 36 weeks' postmenstrual age · patients with preventing morbidity and mortality in very preterm infants

It is very uncertain whether cerebral NIRS oximetry changes chronic lung disease (oxygen supplementation at 36 weeks'… compared with no cerebral NIRS oximetry (very low certainty).

1 finding from 1 review

Cuffed vs uncuffed tubes

Need for tracheal re‐intubation for postoperative stridor (defined as the need to re‐intubate to assure oxygenation to deal with postextubation stridor) · Children up to eight years undergoing general anaesthesia

It is very uncertain whether cuffed changes need for tracheal re‐intubation for postoperative stridor (defined… compared with uncuffed tubes (very low certainty).

1 finding from 1 review

Vitamin A vs no supplementation

Chronic lung disease · promoting growth and development in very low birth weight infants receiving human milk

Supplemental vitamin A showed no clear difference in chronic lung disease (oxygen use at 28 days in survivors) compared with no supplementation (moderate certainty).

2 findings from 1 review

Vitamin A vs no supplementation

Death or chronic lung disease · promoting growth and development in very low birth weight infants receiving human milk

Supplemental vitamin A probably leads to lower death or chronic lung disease (oxygen use at 28 days) compared with no supplementation (moderate certainty).

2 findings from 1 review