Poor oral health-related quality of life (OHRQoL) · Indians
Results were inconsistent and certainty was very low.
1 finding from 1 review
Oral health-related quality of life · Adolescents (10-19 years)
The umbrella review reported no negative oral health-related quality-of-life impact from uncomplicated traumatic dental injuries.
1 finding from 1 review
no estimate extracted
Studies not reported
GRADE not reported
Oral health-related quality of life · Indian elderly
Evidence on functional edentulism and OHRQoL is inconsistent across two studies (very low certainty).
2 findings from 1 review
Functional edentulism vs none: studies show inconsistency; one study found a significant association (Pushpanjali 2013), one did not (Shivakumar 2018); 368 participants, 2 observational studies; Very low certainty (Fig…
2 studies · 368 participants
Very low
SMD 0.31 [-0.37, 0.99]
4 studies · 1146 participants
Very low
Oral health-related quality of life · Adolescents (10-19 years)
Toothache/dental pain is associated with worse OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).
1 finding from 1 review
Oral health-related quality of life · Adolescents (10-19 years)
Access to dental care is associated with better OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).
1 finding from 1 review
Oral health-related quality of life · Adolescents (10-19 years)
The umbrella review reported that traumatic dental injury treatment reduces negative oral health-related quality-of-life impact, based on parental perception.
1 finding from 1 review
no estimate extracted
Studies not reported
GRADE not reported
Oral health-related quality of life · Adolescents (10-19 years)
The umbrella review reported a greater negative oral health-related quality-of-life impact for traumatic injuries involving pulp exposure or tooth darkening.
1 finding from 1 review
no estimate extracted
Studies not reported
GRADE not reported
Oral health-related quality of life · Adolescents (10-19 years)
There is no concrete evidence on the impact of skin color/ethnicity on OHRQoL in adolescents (evidence gap; narrative synthesis; no pooled estimate or GRADE rating).
1 finding from 1 review
Mucosal (oral) hyperpigmentation · Children or adolescents
CLWH on ART had significantly higher prevalence of mucosal hyperpigmentation than healthy controls (pooled OR 20.35, 95% CI 3.86 to 107.39); the authors described the certainty as low.
1 finding from 1 review
Other orofacial opportunistic infections (linear gingival erythema, hairy leukoplakia, angular cheilitis, oral ulcers) · Children and adolescents living with HIV on ART/HAART
ART/HAART duration had minimal influence on the prevalence of orofacial opportunistic infections other than candidiasis (no significant differences).
1 finding from 1 review
Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A Systematic Review… 2022 All outcomesCross-sectional (case-control; single time point) · HIV pediatric/ART clinics, AIDS centers, and hospitals in Brazil, India, Saudi Arabia, and West Africa (Cote d'Ivoire, Mali, Senegal) · ART/HAART duration <3 years vs >=3 years
Except for candidiasis, no significant differences in the prevalence of opportunistic infection manifestations (linear gingival erythema, hairy leukoplakia, angular cheilitis, oral ulcers) between ART duration <3 years…
2 studies
GRADE not reported
Oral health-related quality of life · Children with dental caries
ART and placebo did not differ for oral health-related quality of life, based on an indirect network estimate with no direct trials (MD -0.01, 95% CI -0.40 to 0.38; ungraded).
3 findings from 1 review
HIV-related oral lesions · Children living with HIV receiving ART
One reported study did not show a clear difference in HIV-related oral lesions for children with CD4+ T-cell counts below 250 cells/mm3.
2 findings from 1 review
OR 1.916 [0.613, 2.513]
1 study
GRADE not reported
OR 1.999 [0.129, 3.688]
1 study
GRADE not reported
Recurrent oral ulcerations (WHO clinical stage 2) · Children or adolescents
CLWH on ART had significantly higher prevalence of recurrent oral ulcerations than healthy controls (pooled OR 6.83, 95% CI 1.18 to 39.53).
1 finding from 1 review
Oral candidiasis prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
Oral candidiasis prevalence fell significantly after cART compared with before cART in the same children (very low certainty).
1 finding from 1 review
Oral health-related quality of life · Children with dental caries
The direct estimate found no statistically significant difference in oral health-related quality of life between placebo and silver diamine fluoride.
2 findings from 1 review
Oral hygiene · Children and adolescents (<18 years) living with HIV (CLWH)
Oral hygiene status did not differ significantly between CLWH with and without ART (very low certainty).
1 finding from 1 review
OR 0.73 [0.13, 4.26]
0 studies
GRADE not reported
Intervention not reported
Oral Candida carriage and salivary yeast concentration
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported
Oral health-related quality of life · Children with dental caries
SDF did not significantly differ from placebo for oral health-related quality of life in children (MD 0.03, 95% CI -0.16 to 0.22; ungraded).
1 finding from 1 review
Oral health-related quality of life · Children with dental caries
The direct estimate found no statistically significant difference in oral health-related quality of life between atraumatic restorative treatment plus fluoride varnish and silver diamine fluoride plus fluoride varnish.
2 findings from 1 review
Oral health-related quality of life · Children with dental caries
SDF did not significantly differ from atraumatic restorative treatment for oral health-related quality of life (MD 0.02, 95% CI -0.32 to 0.36; ungraded).
1 finding from 1 review