Question · asked by 1 review

CD4+ T-cell count below 250 cells/mm3: HIV-related oral lesions

Population
Children living with HIV receiving ART
Intervention
CD4+ T-cell count below 250 cells/mm3
Comparison
Not specified
Outcome
HIV-related oral lesions

One reported study did not show a clear difference in HIV-related oral lesions for children with CD4+ T-cell counts below 250 cells/mm3.

What each review found

Include earlier review versions
No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
CD4+ T-cell count below 250 cells/mm3
HIV-related oral lesions · Children living with HIV receiving ART · CD4+ T-cell count below 250 cells/mm3
One reported study did not show a clear difference in HIV-related oral lesions for children with CD4+ T-cell counts below 250 cells/mm3.
Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022) All outcomes
OR 1.916 [0.613, 2.513]1 studyGRADE not reported
CD4+ T-cell count below 250 cells/mm3
HIV-related oral lesions · Children living with HIV receiving ART · CD4+ T-cell count below 250 cells/mm3
One reported study did not show a clear difference in HIV-related oral lesions for children with CD4+ T-cell counts below 250 cells/mm3.
Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022) All outcomes
OR 1.999 [0.129, 3.688]1 studyGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A Systematic Review and Meta-Analysis.
2022 All outcomes
Inception to 29 July 202221Not applicable

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.