Question · asked by 1 review
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls: Mucosal (oral) hyperpigmentation
- Population
- Children or adolescents
- Intervention
- Living with HIV and undergoing antiretroviral therapy (ART/HAART)
- Comparison
- Healthy HIV-negative controls
- Outcome
- Mucosal (oral) hyperpigmentation
CLWH on ART had significantly higher prevalence of mucosal hyperpigmentation than healthy controls (pooled OR 20.35, 95% CI 3.86 to 107.39); the authors described the certainty as low.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls Mucosal (oral) hyperpigmentation · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point), HIV pediatric/ART clinics, AIDS centers, and hospitals in Brazil, India, Saudi Arabia, and West Africa (Cote d'Ivoire, Mali, Senegal) CLWH on ART had significantly higher prevalence of mucosal hyperpigmentation than healthy controls (pooled OR 20.35, 95% CI 3.86 to 107.39); the authors described the certainty as low. Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A… (2022) All outcomes | OR 20.35 [3.86, 107.39] | 3 studies · 407 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A Systematic Review and Meta-Analysis. 2022 All outcomes | Inception to 29 July 2022 | 21 | Not applicable |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.