evidencegaps
Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

8 questions · 9 findings · 8 reviews · Neonatal

Sort:Best matchNewestHighest certaintyDownload CSV
No studies found 1 · 11.1%GRADE not reported 0 · 0%Very low 5 · 55.6%Low 2 · 22.2%Moderate 1 · 11.1%High 0 · 0%

Bubble vs ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP)

Treatment failure · preterm infants receiving nasal CPAP

Bubble may leads to lower treatment failure compared with ventilator or Infant Flow Driver nasal continuous positive airway… (low certainty).

1 finding from 1 review

HFNC vs continuous positive airway pressure (CPAP)

Treatment failure · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))

It is very uncertain whether summary of findings table ‐ High flow nasal cannula (HFNC) changes treatment failure compared with continuous positive airway pressure (CPAP) (very low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Low vs moderate‐high nasal continuous positive airway pressure levels

Treatment failure or need for mechanical ventilation · health problem or population

It is very uncertain whether summary of Findings Table ‐ Low changes treatment failure or need for mechanical ventilation compared with moderate‐high nasal continuous positive airway pressure levels (very low certainty).

2 findings from 1 review

Early vs late continuous positive airway pressure (CPAP)

Failure of treatment ‐ death or intermittent positive‐pressure ventilation (IPPV) before hospital discharge · preterm infants with respiratory distress for initial respiratory support

The review found no eligible studies for this question.

1 finding from 1 review

HFNC vs continuous positive airway pressure (CPAP)

Treatment failure within 72 hours of trial entry · preterm infants requiring primary respiratory support

Nasal high flow probably leads to higher treatment failure within 72 hours of trial entry compared with continuous positive airway pressure (moderate certainty).

1 finding from 1 review

Continuous positive airway pressure (CPAP) vs supplemental oxygen

Treatment failure (death or use of additional ventilatory support) · preterm infants with respiratory distress for initial respiratory support

It is very uncertain whether CPAP changes treatment failure (death or use of additional ventilatory support) compared with supplemental oxygen (very low certainty).

1 finding from 1 review