Cochrane · systematic review · CD008168
Intermittent phototherapy versus continuous phototherapy for neonatal jaundice
Gottimukkala, SB, Lobo, L, Gautham, KS, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 50%Low 2 · 50%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Intermittent phototherapy compared to continuous phototherapy for neonatal jaundice
Population: neonatal jaundice
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Rate of decline of serum bilirubin (micromol/L/hr) Intermittent phototherapy vs continuous phototherapy | no estimate extracted | 10 studies · 1225 participants | Low Downgraded: inconsistency |
Bilirubin‐induced brain dysfunction (defined as either the pathological finding of deep‐yellow staining of neurons and neuronal necrosis of the basal ganglia and brainstem nuclei or acute or chronic neurological deficit including athetoid cerebral... Intermittent phototherapy vs continuous phototherapy | no estimate extracted | 1 study · 60 participants | Very low Downgraded: imprecision, inconsistency |
Treatment failure (need to restart phototherapy or exchange transfusion or both) Intermittent phototherapy vs continuous phototherapy | no estimate extracted | 1 study · 75 participants | Very low Downgraded: imprecision, inconsistency |
Mortality (all cause) Intermittent phototherapy vs continuous phototherapy | no estimate extracted | 10 studies · 1470 participants | Low Downgraded: imprecision, inconsistency |