Cochrane · systematic review · CD015130
Bubble devices versus other pressure sources for nasal continuous positive airway pressure in preterm infants
Prakash, R, De Paoli, AG, Davis, PG, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
5
No studies
1
Included studies
NR
No studies 1 · 16.7%Ungraded 0 · 0%Very low 0 · 0%Low 4 · 66.7%Moderate 1 · 16.7%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Bubble versus ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP) for preterm infants
Population: preterm infants receiving nasal CPAP
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Treatment failure Bubble vs ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP) | RR 0.76 [0.6, 0.95] | 13 studies · 1230 participants | Low Downgraded: risk of bias, imprecision |
All‐cause mortality before hospital discharge Bubble vs ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP) | RR 0.93 [0.64, 1.36] | 10 studies · 1189 participants | Low Downgraded: risk of bias, imprecision |
Neurodevelopmental impairment Bubble vs ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP) | no estimate extracted | NR | No studies |
Pneumothorax Bubble vs ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP) | RR 0.73 [0.4, 1.34] | 14 studies · 1340 participants | Low Downgraded: risk of bias, imprecision |
Moderate‐severe nasal injury Bubble vs ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP) | RR 2.29 [1.37, 3.82] | 8 studies · 753 participants | Moderate Downgraded: risk of bias |
Bronchopulmonary dysplasia Bubble vs ventilator or Infant Flow Driver nasal continuous positive airway pressure (CPAP) | RR 0.76 [0.53, 1.1] | 7 studies · 603 participants | Low Downgraded: risk of bias, imprecision |