Findings

What do systematic reviews say?

59 questions · 63 findings · 26 reviews · Headline outcomes only

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No studies found 40 · 63.5%GRADE not reported 3 · 4.8%Very low 4 · 6.3%Low 7 · 11.1%Moderate 6 · 9.5%High 3 · 4.8%

Oral antibiotics vs IV antibiotics

Quality of life · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

The review found no eligible studies for this question.

1 finding from 1 review

Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Nebulised antibiotics vs IV antibiotics

Quality of life · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

The review found no eligible studies for this question.

1 finding from 1 review

Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs placebo or no intervention

Quality of life at maximum · patients with coronary heart disease

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for secondary prevention of coronary heart disease 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs placebo or no intervention

Quality of life at 24±6 months · patients with coronary heart disease

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for secondary prevention of coronary heart disease 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs placebo

Disease‐specific quality of life · children aged 6 months to 12 years with otitis media with effusion (OME)

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for otitis media with effusion (OME) in children 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment

Disease‐specific quality of life · children aged 6 months to 12 years with otitis media with effusion (OME)

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for otitis media with effusion (OME) in children 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs systemic antibiotics

Quality of life · bacterial folliculitis and boils (furuncles and carbuncles)

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for bacterial folliculitis and boils (furuncles and carbuncles) 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs placebo

Quality of life and activity impairment · patients with uncomplicated acute maxillary sinusitis

1 finding from 1 review

Antibiotics for acute maxillary sinusitis in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Antibiotics vs no treatment or placebo on top of topical antibiotics

Health‐related quality of life · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment or placebo on top of topical antibiotics

Health‐related quality of life ‐ unclear · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 101 participants
Very low

Oral antibiotics vs placebo

Quality of life measures · adult participants with chronic blepharitis

The review found no eligible studies for this question.

1 finding from 1 review

Oral antibiotics for chronic blepharitis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics with steroids vs topical antibiotics

Health‐related quality of life · people (of any age) with chronic suppurative otitis media or ear discharge

The review found no eligible studies for this question.

2 findings from 1 review

Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs antiseptic agent

Quality of life · bacterial folliculitis and boils (furuncles and carbuncles)

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for bacterial folliculitis and boils (furuncles and carbuncles) 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs placebo/no treatment

Health‐related quality of life · patients with mucopurulent otorrhoea

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs acetic acid

Quality of life ‐ not measured · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment or placebo on top of topical antiseptics

Health‐related quality of life · schoolchildren with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment/placebo

Health‐related quality of life · children with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: Inhaled antibiotics vs IV antibiotics

Quality of life perceived change in lifestyle after treatment · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

1 finding from 1 review

Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Very low

Summary of findings: Inhaled antibiotics plus IV antibiotics vs IV antibiotics

Quality of life: number of participants achieving MCID · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

Summary of findings: Inhaled antibiotics plus IV antibiotics showed no clear difference in quality of life: number of participants achieving MCID compared with IV antibiotics only (low certainty).

1 finding from 1 review

Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis 2022 · Cochrane Headline outcomes only
RR 1.2 [0.61, 2.34]
1 study · 16 participants
Low

Antibiotics vs other antibiotics

Quality of life ‐ not reported · farmworkers

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis for leptospirosis 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found