Findings

What do systematic reviews say?

29 questions · 29 findings · 20 reviews · Headline outcomes only

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No studies found 8 · 27.6%GRADE not reported 2 · 6.9%Very low 10 · 34.5%Low 6 · 20.7%Moderate 3 · 10.3%High 0 · 0%

Radiosurgery alone vs WBRT and radiosurgery

Quality of lifeNo. of participants: 271(2 RCTs) · patients with newly diagnosed multiple brain metastases

1 finding from 1 review

Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Acupuncture as an addition to the routine primary care that trial participants were receiving from their physicians vs routine primary physician care alone

Quality of life (mental component) (short‐term) SF‐36 physical component scale from 0 to 100 (higher is better quality of life). · patients with hip osteoarthritis

1 finding from 1 review

Acupuncture for hip osteoarthritis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 137 participants
Low

Acupuncture as an addition to the routine primary care that trial participants were receiving from their physicians vs routine primary physician care alone

Quality of Life: SF‐36 (physical component) · patients with hip osteoarthritis

1 finding from 1 review

Acupuncture for hip osteoarthritis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 137 participants
Low

Shengmai plus usual treatment vs usual treatment alone

Mean change in quality of life Minnesota Living with Heart Failure Questionnaire (MLWHF) score · patients with heart failure

1 finding from 1 review

Shengmai (a traditional Chinese herbal medicine) for heart failure 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Low

Microwave coagulation in addition to conventional transarterial chemoembolisation vs chemoembolisation

Health‐related quality of life · people with liver metastases

The review found no eligible studies for this question.

1 finding from 1 review

Microwave coagulation for liver metastases 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Continuous chest compression alone vs interrupted chest compression plus artificial ventilation

Quality of life · Patients with non‐trauma related out‐of‐hospital cardiac arrest

1 finding from 1 review

Continuous chest compression versus interrupted chest compression for cardiopulmonary resuscitation of non‐asphyxial… 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Summary of findings ‐ Exercise alone vs exercise plus electrophysical modality

Quality of life · participants with haemophilia

The review found no eligible studies for this question.

1 finding from 1 review

Exercise for haemophilia 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Laxative plus bulking agent vs laxative alone

Quality of life · postpartum women who underwent surgical repair of third degree perineal tears

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

External beam radiotherapy (EBRT) plus transarterial chemoembolisation (TACE) vs TACE alone

Health‐related quality of life · participants with unresectable hepatocellular carcinoma

The review found no eligible studies for this question.

1 finding from 1 review

External beam radiotherapy for unresectable hepatocellular carcinoma 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

WBRT with radiosensitisers (radiosen) vs WBRT

Quality of lifeNo. of participants: 271(2 RCTs) · patients with newly diagnosed multiple brain metastases

1 finding from 1 review

Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Health‐related quality of life · people with symptomatic intracranial artery stenosis

The review found no eligible studies for this question.

1 finding from 1 review

Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone

Quality of life · people with venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table (subcomparison 2): second‐line chemotherapy or targeted therapy agent(s) plus control intervention vs control intervention

Quality of life · palliative participants with esophageal and GE‐junction carcinoma previously treated with chemotherapy

1 finding from 1 review

Palliative chemotherapy and targeted therapies for esophageal and gastroesophageal junction cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1638 participants
Very low

Summary of findings table (subcomparison 3): chemotherapy agent(s) plus control intervention vs control intervention

Quality of life · palliative participants with esophageal and GE‐junction carcinoma

1 finding from 1 review

Palliative chemotherapy and targeted therapies for esophageal and gastroesophageal junction cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
450 participants
Very low

Summary of findings table (subcomparison 4): targeted therapy agent plus control intervention vs control intervention

Quality of life · palliative participants with esophageal and GE‐junction carcinoma

1 finding from 1 review

Palliative chemotherapy and targeted therapies for esophageal and gastroesophageal junction cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 2054 participants
Very low

Summary of findings table (subcomparison 5): chemotherapy or targeted therapy agent(s) plus control intervention vs control intervention

Quality of life · palliative participants with AC of the esophagus

1 finding from 1 review

Palliative chemotherapy and targeted therapies for esophageal and gastroesophageal junction cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1772 participants
Very low

Summary of findings table (subcomparison 5): chemotherapy or targeted therapy agent(s) plus control intervention vs control intervention

Quality of life · palliative participants with SCC of the esophagus

1 finding from 1 review

Palliative chemotherapy and targeted therapies for esophageal and gastroesophageal junction cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 156 participants
Very low

Summary of findings table (subcomparison 5): chemotherapy or targeted therapy agent(s) plus control intervention vs control intervention

Quality of life · palliative participants with esophageal and GE‐junction carcinoma

1 finding from 1 review

Palliative chemotherapy and targeted therapies for esophageal and gastroesophageal junction cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1870 participants
Very low

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Quality of life ‐ after 48 months Number of participants: 1325(1 RCT)

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Does treatment guided by serial BNP or NT‐proBNP monitoring improve outcomes vs treatment guided by clinical assessment alone?

Quality of life (MLHFQ): from 0 to 105 · patients with heart failure

1 finding from 1 review

B‐type natriuretic peptide‐guided treatment for heart failure 2016 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1812 participants
Very low