Cochrane · systematic review · CD011180

Exercise for haemophilia

Strike, K, Mulder, K, Michael, R · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
25
current version
GRADE rated
12
No studies
13
Included studies
NR
No studies 13 · 52%Ungraded 0 · 0%Very low 8 · 32%Low 3 · 12%Moderate 1 · 4%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings ‐ Exercise compared with no intervention

Population: participants with haemophilia
7 questions
OutcomeEffectEvidenceStatus / GRADE
Adverse events
Summary of findings ‐ Exercise vs no intervention
no estimate extractedNRNo studies
Quality of life
Summary of findings ‐ Exercise vs no intervention
no estimate extractedNRNo studies
Joint health: Modified Colorado Score
Summary of findings ‐ Exercise vs no intervention
no estimate extracted1 study · 25 participantsLow
Downgraded: risk of bias, imprecision, indirectness
Pain: reduction of pain intensity by visual analogue scale
Summary of findings ‐ Exercise vs no intervention
no estimate extracted1 study · 18 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Functional Status
Summary of findings ‐ Exercise vs no intervention
no estimate extractedNRNo studies
Range of Motion: joint flexion and joint extension
Summary of findings ‐ Exercise vs no intervention
no estimate extracted1 study · 18 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Strength: bicep strength
Summary of findings ‐ Exercise vs no intervention
no estimate extracted1 study · 18 participantsVery low
Downgraded: risk of bias, imprecision, indirectness

Summary of findings ‐ Exercise A compared with Exercise B

Population: participants with haemophilia
7 questions
OutcomeEffectEvidenceStatus / GRADE
Adverse events
Summary of findings ‐ Exercise A vs Exercise B
no estimate extractedNRNo studies
Quality of life
Summary of findings ‐ Exercise A vs Exercise B
no estimate extractedNRNo studies
Balance: Biodex stability parameters
Summary of findings ‐ Exercise A vs Exercise B
no estimate extracted1 study · 30 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Pain: reduction of pain intensity by visual analogue scale
Summary of findings ‐ Exercise A vs Exercise B
no estimate extracted1 study · 27 participantsLow
Downgraded: risk of bias, imprecision, indirectness
Functional Status: 6MWT (metres)
Summary of findings ‐ Exercise A vs Exercise B
no estimate extracted1 study · 30 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Range of Motion: flexion and extension
Summary of findings ‐ Exercise A vs Exercise B
no estimate extracted1 study · 27 participantsLow
Downgraded: risk of bias, imprecision, indirectness
Strength: flexors and extensors
Summary of findings ‐ Exercise A vs Exercise B
no estimate extracted3 studies · 90 participantsModerate
Downgraded: risk of bias, imprecision, indirectness

Summary of findings ‐ Exercise alone compared with exercise plus electrophysical modality

Population: participants with haemophilia
5 questions
OutcomeEffectEvidenceStatus / GRADE
Adverse events
Summary of findings ‐ Exercise alone vs exercise plus electrophysical modality
no estimate extractedNRNo studies
Quality of life
Summary of findings ‐ Exercise alone vs exercise plus electrophysical modality
no estimate extractedNRNo studies
Pain
Summary of findings ‐ Exercise alone vs exercise plus electrophysical modality
no estimate extractedNRNo studies
Functional Status
Summary of findings ‐ Exercise alone vs exercise plus electrophysical modality
no estimate extractedNRNo studies
Joint health: Modified Colorado Score
Summary of findings ‐ Exercise alone vs exercise plus electrophysical modality
no estimate extracted1 study · 25 participantsVery low
Downgraded: risk of bias, imprecision, indirectness

Summary of findings ‐ Hydrotherapy compared with no exercise

Population: participants with haemophilia
6 questions
OutcomeEffectEvidenceStatus / GRADE
Adverse events
Summary of findings ‐ Hydrotherapy vs no exercise
no estimate extractedNRNo studies
Quality of life
Summary of findings ‐ Hydrotherapy vs no exercise
no estimate extractedNRNo studies
Pain
Summary of findings ‐ Hydrotherapy vs no exercise
no estimate extractedNRNo studies
Functional status
Summary of findings ‐ Hydrotherapy vs no exercise
no estimate extractedNRNo studies
Range of motion: flexion and extension
Summary of findings ‐ Hydrotherapy vs no exercise
no estimate extracted1 study · 20 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Strength: knee flexor and extensor strength
Summary of findings ‐ Hydrotherapy vs no exercise
no estimate extracted1 study · 20 participantsVery low
Downgraded: risk of bias, imprecision, indirectness