Cochrane · systematic review · CD012164
Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers
Lin, ZC, Loveland, PM, Johnston, RV, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
WoundsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
18
current version
GRADE rated
8
No studies
10
Included studies
NR
No studies 10 · 55.6%Ungraded 0 · 0%Very low 7 · 38.9%Low 1 · 5.6%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Subfascial endoscopic perforator vein surgery (SEPS) + compression versus compression alone for treating venous leg ulcers
Population: participants with venous leg ulcers
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Proportion with ulcers healed at 24 months Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone | RR 1.17 [1.03, 1.33] | 1 study · 196 participants | Low Downgraded: risk of bias, imprecision |
Time to complete healing Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone | no estimate extracted | NR | No studies |
Ulcer recurrence at 24 months Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone | RR 0.85 [0.26, 2.76] | 2 studies · 208 participants | Very low Downgraded: risk of bias, imprecision |
Quality of life Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone | no estimate extracted | NR | No studies |
Adverse events Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone | no estimate extracted | NR | No studies |
Pain Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone | no estimate extracted | NR | No studies |
Subfascial endoscopic perforator vein surgery (SEPS) compared to the Linton procedure for treating venous leg ulcers
Population: participants with venous leg ulcers
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Proportion of ulcers healed at 24 months Subfascial endoscopic perforator vein surgery (SEPS) vs the Linton procedure | RR 0.95 [0.83, 1.09] | 1 study · 39 participants | Very low Downgraded: risk of bias, imprecision |
Time to complete healing Subfascial endoscopic perforator vein surgery (SEPS) vs the Linton procedure | no estimate extracted | NR | No studies |
Ulcer recurrence at 60 months Subfascial endoscopic perforator vein surgery (SEPS) vs the Linton procedure | RR 0.47 [0.1, 2.3] | 1 study · 39 participants | Very low Downgraded: risk of bias, imprecision |
Quality of life Subfascial endoscopic perforator vein surgery (SEPS) vs the Linton procedure | no estimate extracted | NR | No studies |
Adverse events2 Subfascial endoscopic perforator vein surgery (SEPS) vs the Linton procedure | RR 0.04 [0, 0.6] | 1 study · 39 participants | Very low Downgraded: risk of bias, imprecision |
Pain Subfascial endoscopic perforator vein surgery (SEPS) vs the Linton procedure | no estimate extracted | NR | No studies |
Subfascial endoscopic perforator vein surgery (SEPS) + saphenous surgery compared to saphenous surgery for treating venous leg ulcers
Population: participants with venous leg ulcers
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Proportion of ulcers healed at 12 months Subfascial endoscopic perforator vein surgery (SEPS) + saphenous surgery vs saphenous surgery | RR 0.96 [0.64, 1.43] | 1 study · 22 participants | Very low Downgraded: risk of bias, imprecision |
Time to complete healing Subfascial endoscopic perforator vein surgery (SEPS) + saphenous surgery vs saphenous surgery | no estimate extracted | NR | No studies |
Ulcer recurrence at 12 months Subfascial endoscopic perforator vein surgery (SEPS) + saphenous surgery vs saphenous surgery | RR 1.03 [0.15, 6.91] | 1 study · 75 participants | Very low Downgraded: risk of bias, imprecision |
Quality of life Subfascial endoscopic perforator vein surgery (SEPS) + saphenous surgery vs saphenous surgery | no estimate extracted | NR | No studies |
Adverse events Subfascial endoscopic perforator vein surgery (SEPS) + saphenous surgery vs saphenous surgery | RR 2.05 [0.86, 4.9] | 1 study · 75 participants | Very low Downgraded: risk of bias, imprecision |
Pain Subfascial endoscopic perforator vein surgery (SEPS) + saphenous surgery vs saphenous surgery | no estimate extracted | NR | No studies |