Cochrane · systematic review · CD013267

Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis

Luo, J, Wang, T, Yang, K, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

Stroke2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
2
Included studies
NR
No studies 2 · 28.6%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 14.3%Moderate 4 · 57.1%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

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Endovascular therapy plus conventional medical treatment compared to conventional medical treatment alone for symptomatic intracranial artery stenosis

Population: people with symptomatic intracranial artery stenosis
7 questions
OutcomeEffectEvidenceStatus / GRADE
Death or stroke
Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone
RR 2.93 [1.81, 4.75]4 studies · 989 participantsModerate
Downgraded: imprecision
Ipsilateral stroke
Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone
RR 3.26 [1.94, 5.48]4 studies · 989 participantsModerate
Downgraded: imprecision
Type of recurrent event
Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone
RR 0.79 [0.3, 2.07]3 studies · 344 participantsModerate
Downgraded: imprecision
Death
Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone
RR 5.43 [1.21, 24.4]4 studies · 989 participantsLow
Downgraded: imprecision
Dependency
Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone
RR 1.51 [0.93, 2.45]4 studies · 947 participantsModerate
Downgraded: imprecision
Restenosis (≥ 50%)
Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone
no estimate extractedNRNo studies
Health‐related quality of life
Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone
no estimate extractedNRNo studies