Cochrane · systematic review · CD013267
Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis
Luo, J, Wang, T, Yang, K, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
2
Included studies
NR
No studies 2 · 28.6%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 14.3%Moderate 4 · 57.1%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyEndovascular therapy plus conventional medical treatment compared to conventional medical treatment alone for symptomatic intracranial artery stenosis
Population: people with symptomatic intracranial artery stenosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death or stroke Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone | RR 2.93 [1.81, 4.75] | 4 studies · 989 participants | Moderate Downgraded: imprecision |
Ipsilateral stroke Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone | RR 3.26 [1.94, 5.48] | 4 studies · 989 participants | Moderate Downgraded: imprecision |
Type of recurrent event Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone | RR 0.79 [0.3, 2.07] | 3 studies · 344 participants | Moderate Downgraded: imprecision |
Death Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone | RR 5.43 [1.21, 24.4] | 4 studies · 989 participants | Low Downgraded: imprecision |
Dependency Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone | RR 1.51 [0.93, 2.45] | 4 studies · 947 participants | Moderate Downgraded: imprecision |
Restenosis (≥ 50%) Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone | no estimate extracted | NR | No studies |
Health‐related quality of life Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone | no estimate extracted | NR | No studies |
Endovascular therapy compared to conventional medical treatment for symptomatic intracranial artery stenosis
Population: symptomatic intracranial artery stenosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death or stroke Endovascular therapy vs conventional medical treatment | RR 3.07 [1.8, 5.24] | 3 studies · 632 participants | Moderate Downgraded: imprecision |
Ipsilateral stroke Endovascular therapy vs conventional medical treatment | RR 3.54 [1.98, 6.33] | 3 studies · 632 participants | Moderate Downgraded: imprecision |
Type of recurrent event Endovascular therapy vs conventional medical treatment | RR 0.52 [0.11, 2.35] | 2 studies · 181 participants | Moderate Downgraded: imprecision |
Death Endovascular therapy vs conventional medical treatment | RR 5.53 [0.98, 31.17] | 3 studies · 632 participants | Low Downgraded: imprecision |
Dependency Endovascular therapy vs conventional medical treatment | RR 1.9 [0.91, 3.97] | 3 studies · 613 participants | Moderate Downgraded: imprecision |
Restenosis (≥ 50%) Endovascular therapy vs conventional medical treatment | no estimate extracted | NR | No studies |
Health‐related quality of life Endovascular therapy vs conventional medical treatment | no estimate extracted | NR | No studies |