Cochrane · systematic review · CD012889
Non‐invasive positive pressure ventilation for central sleep apnoea in adults
Pinto, ACPereira Nunes, Rocha, A, Drager, LF, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
48
current version
GRADE rated
18
No studies
30
Included studies
NR
No studies 30 · 62.5%Ungraded 0 · 0%Very low 3 · 6.3%Low 14 · 29.2%Moderate 1 · 2.1%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Continuous positive airway pressure (CPAP) plus best supportive care versus best supportive care for central sleep apnoea associated with chronic heart failure
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Central AHI ‐ after 3 months Number of participants: 205(1 RCT) Continuous positive airway pressure (CPAP) plus best supportive care vs best supportive care | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Cardiovascular mortality ‐ after 24 months Number of participants: 258(1 RCT) Continuous positive airway pressure (CPAP) plus best supportive care vs best supportive care | RR 1.17 [0.68, 2.02] | NR | Low Downgraded: risk of bias, imprecision |
Serious adverse events Continuous positive airway pressure (CPAP) plus best supportive care vs best supportive care | no estimate extracted | NR | No studies |
Quality of sleep Continuous positive airway pressure (CPAP) plus best supportive care vs best supportive care | no estimate extracted | NR | No studies |
Quality of life Continuous positive airway pressure (CPAP) plus best supportive care vs best supportive care | no estimate extracted | NR | No studies |
AHI ‐ after up to 3 months Number of participants: 264(4 RCT) Continuous positive airway pressure (CPAP) plus best supportive care vs best supportive care | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
All‐cause mortality ‐ after 24 months Number of participants: 287(2 RCTs) Continuous positive airway pressure (CPAP) plus best supportive care vs best supportive care | RR 1.14 [0.83, 1.56] | NR | Very low Downgraded: risk of bias, imprecision |
Time to life‐saving cardiovascular intervention ( Continuous positive airway pressure (CPAP) plus best supportive care vs best supportive care | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Adaptive servo ventilation (ASV) versus continuous positive airway pressure (CPAP) for central sleep apnoea associated with chronic heart failure
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Central AHI Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP) | no estimate extracted | NR | No studies |
Cardiovascular mortality Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP) | no estimate extracted | NR | No studies |
Serious adverse events Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP) | no estimate extracted | NR | No studies |
Quality of sleep Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP) | no estimate extracted | NR | No studies |
Quality of life Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP) | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
AHI ‐ after 6 months Number of participants: 17(1 RCT) Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP) | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
All‐cause mortality Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP) | no estimate extracted | NR | No studies |
Time to life‐saving cardiovascular intervention Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP) | no estimate extracted | NR | No studies |
Adaptive servo ventilation (ASV) versus bilevel ventilation for central sleep apnoea associated with chronic heart failure
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Central AHI ‐ after 6 weeks Number of participants: 30(1 RCT) Adaptive servo ventilation (ASV) vs bilevel ventilation | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Cardiovascular mortality Adaptive servo ventilation (ASV) vs bilevel ventilation | no estimate extracted | NR | No studies |
Serious adverse events Adaptive servo ventilation (ASV) vs bilevel ventilation | no estimate extracted | NR | No studies |
Quality of sleep Adaptive servo ventilation (ASV) vs bilevel ventilation | no estimate extracted | NR | No studies |
Quality of life Adaptive servo ventilation (ASV) vs bilevel ventilation | no estimate extracted | NR | No studies |
AHI ‐ after 6 weeks Number of participants: 30(1 RCT) Adaptive servo ventilation (ASV) vs bilevel ventilation | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
All‐cause mortality Adaptive servo ventilation (ASV) vs bilevel ventilation | no estimate extracted | NR | No studies |
Time to life‐saving cardiovascular intervention Adaptive servo ventilation (ASV) vs bilevel ventilation | no estimate extracted | NR | No studies |
Adaptive servo ventilation (ASV) versus continuous positive airway pressure (CPAP) for CPAP‐induced central sleep apnoea
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Central AHI ‐ after 3 months Number of participants: 60(1 RCT) Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP) | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Cardiovascular mortality Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP) | no estimate extracted | NR | No studies |
Serious adverse events Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP) | no estimate extracted | NR | No studies |
Quality of sleep Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP) | no estimate extracted | NR | No studies |
Quality of life ‐ after 3 months Number of participants: 61(1 RCT) Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP) | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
AHI ‐ after 3 months Number of participants: 60(1 RCT) Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP) | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
All‐cause mortality Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP) | no estimate extracted | NR | No studies |
Time to life‐saving cardiovascular intervention Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP) | no estimate extracted | NR | No studies |
Adaptive servo ventilation (ASV) versus bilevel ventilation for CPAP‐induced central sleep apnoea
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Central AHI ‐ after 6 weeks Number of participants: 30(1 RCT) Adaptive servo ventilation (ASV) vs bilevel ventilation | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Cardiovascular mortality Adaptive servo ventilation (ASV) vs bilevel ventilation | no estimate extracted | NR | No studies |
Serious adverse events Adaptive servo ventilation (ASV) vs bilevel ventilation | no estimate extracted | NR | No studies |
Quality of sleep Adaptive servo ventilation (ASV) vs bilevel ventilation | no estimate extracted | NR | No studies |
Quality of life Adaptive servo ventilation (ASV) vs bilevel ventilation | no estimate extracted | NR | No studies |
AHI ‐ after 6 weeks Number of participants: 30(1 RCT) Adaptive servo ventilation (ASV) vs bilevel ventilation | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
All‐cause mortality Adaptive servo ventilation (ASV) vs bilevel ventilation | no estimate extracted | NR | No studies |
Time to life‐saving cardiovascular intervention Adaptive servo ventilation (ASV) vs bilevel ventilation | no estimate extracted | NR | No studies |
Adaptive servo ventilation (ASV) plus best supportive care versus best supportive care alone or inactive control for central sleep apnoea associated with chronic heart failure
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Central AHI Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control | no estimate extracted | NR | No studies |
Cardiovascular mortality ‐ up to 80 months Number of participants: 1325(1 RCT) Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control | RR 1.25 [1.04, 1.49] | NR | Moderate Downgraded: risk of bias, imprecision |
Serious adverse events Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control | no estimate extracted | NR | No studies |
Quality of sleep Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control | no estimate extracted | NR | No studies |
Quality of life ‐ after 48 months Number of participants: 1325(1 RCT) Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
AHI ‐ after 6 months Number of participants: 30(1 RCT) Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
All‐cause mortality ‐ up to 80 months Number of participants: 1355(2 RCTs) Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control | RR 0.56 [0.06, 4.93] | NR | Low Downgraded: risk of bias, imprecision |
Time to life‐saving cardiovascular intervention Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control | no estimate extracted | NR | No studies |