Findings

What do systematic reviews say?

10 questions · 10 findings · 4 reviews · Pregnancy and Childbirth

Sort:Best matchNewest Highest certainty Download CSV

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 5 · 50%Low 4 · 40%Moderate 1 · 10%High 0 · 0%

Antibiotics vs antibiotics alone

Neonatal sepsis · women in labor with management of intra‐amniotic infection

Antibiotics showed no clear difference in neonatal sepsis compared with antibiotics (low certainty).

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
RR 1.07 [0.4, 2.86]
2 studies · 163 participants
Low

Antibiotics vs placebo

Neonatal sepsis · Women with meconium‐stained amniotic fluid in labour, gestational age more than 24 weeks

Antibiotic showed no clear difference in neonatal sepsis compared with placebo (low certainty).

1 finding from 1 review

Antibiotics for meconium‐stained amniotic fluid in labour for preventing maternal and neonatal infections 2014 · Cochrane Headline outcomes only
RR 1 [0.21, 4.76]
1 study · 120 participants
Low

Antibiotics vs no treatment during postpartum period

Neonatal sepsis · women with management of intra‐amniotic infection

It is very uncertain whether antibiotics changes neonatal sepsis compared with no treatment during postpartum period (very low certainty).

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
RR 1.11 [0.23, 5.27]
1 study · 55 participants
Very low

Antibiotics vs placebo or no antibiotic

Probable early‐onset neonatal sepsis ‐ Late induction of labour · pregnant women with prelabour rupture of membranes at or near term

It is very uncertain whether any antibiotic changes probable early‐onset neonatal sepsis ‐ Late induction of labour compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (very low certainty).

1 finding from 1 review

Antibiotics for prelabour rupture of membranes at or near term 2014 · Cochrane Headline outcomes only
RR 0.14 [0.02, 1.13]
2 studies · 838 participants
Very low

Antibiotics vs placebo or no antibiotic

Definite early‐onset neonatal sepsis ‐ Late induction of labour · pregnant women with prelabour rupture of membranes at or near term

It is very uncertain whether any antibiotic changes definite early‐onset neonatal sepsis ‐ Late induction of labour compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (very low certainty).

1 finding from 1 review

Antibiotics for prelabour rupture of membranes at or near term 2014 · Cochrane Headline outcomes only
RR 0.16 [0.02, 1.34]
2 studies · 838 participants
Very low

Antibiotics vs placebo or no antibiotic

Probable early‐onset neonatal sepsis ‐ Early induction of labour · pregnant women with prelabour rupture of membranes at or near term

Any antibiotic showed no clear difference in probable early‐onset neonatal sepsis ‐ Early induction of labour compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (low certainty).

1 finding from 1 review

Antibiotics for prelabour rupture of membranes at or near term 2014 · Cochrane Headline outcomes only
RR 1.47 [0.8, 2.7]
1 study · 1640 participants
Low

Antibiotics vs placebo or no antibiotic

Definite early‐onset neonatal sepsis ‐ Early induction of labour · pregnant women with prelabour rupture of membranes at or near term

Any antibiotic showed no clear difference in definite early‐onset neonatal sepsis ‐ Early induction of labour compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (low certainty).

1 finding from 1 review

Antibiotics for prelabour rupture of membranes at or near term 2014 · Cochrane Headline outcomes only
RR 1.29 [0.48, 3.44]
1 study · 1640 participants
Low

Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping

Neonatal sepsis · women undergoing caesarean section

Prophylactic intravenous antibiotics administered before cesarean… showed no clear difference in neonatal sepsis compared with after neonatal umbilical cord clamping (moderate certainty).

1 finding from 1 review

Timing of intravenous prophylactic antibiotics for preventing postpartum infectious morbidity in women undergoing… 2014 · Cochrane Headline outcomes only
RR 0.76 [0.51, 1.13]
5 studies · 2907 participants
Moderate

Intrapartum vs postpartum treatment

Early neonatal sepsis · women with management of intra‐amniotic infection

It is very uncertain whether intrapartum changes early neonatal sepsis compared with postpartum treatment (very low certainty).

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
RR 0.08 [0, 1.44]
1 study · 45 participants
Very low

Intrapartum vs postpartum treatment

Neonatal pneumonia or sepsis · women with management of intra‐amniotic infection

It is very uncertain whether intrapartum changes neonatal pneumonia or sepsis compared with postpartum treatment (very low certainty).

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
RR 0.06 [0, 0.95]
1 study · 45 participants
Very low