Question · asked by 1 review
Antibiotics vs placebo: Neonatal sepsis
- Population
- Women with meconium‐stained amniotic fluid in labour, gestational age more than 24 weeks
- Intervention
- Antibiotics
- Comparison
- placebo
- Outcome
- Neonatal sepsis
Antibiotic showed no clear difference in neonatal sepsis compared with placebo (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Antibiotic vs placebo Neonatal sepsis · Women with meconium‐stained amniotic fluid in labour, gestational age more than 24 weeks Antibiotic showed no clear difference in neonatal sepsis compared with placebo (low certainty). Antibiotics for meconium‐stained amniotic fluid in labour for preventing maternal and neonatal infections (2014) · Cochrane Headline outcomes only | RR 1 [0.21, 4.76] | 1 study · 120 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Antibiotics for meconium‐stained amniotic fluid in labour for preventing maternal and neonatal infections 2014 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Antibiotics vs antibiotics alone · women in labor with management of intra‐amniotic infection · 1 review
- Antibiotics vs no treatment during postpartum period · women with management of intra‐amniotic infection · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.