Cochrane · systematic review · CD009516
Timing of intravenous prophylactic antibiotics for preventing postpartum infectious morbidity in women undergoing cesarean delivery
Mackeen, AD, Packard, RE, Ota, E, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 14.3%Moderate 2 · 28.6%High 4 · 57.1%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Prophylactic intravenous antibiotics administered before cesarean incision versus after neonatal umbilical cord clamping
Population: women undergoing cesarean delivery.
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Maternal composite morbidity Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping | RR 0.67 [0.54, 0.82] | 10 studies · 5041 participants | High |
Maternal endomyometritis Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping | RR 0.54 [0.36, 0.79] | 10 studies · 5041 participants | High |
Maternal wound Infection Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping | RR 0.59 [0.44, 0.81] | 10 studies · 5041 participants | High |
Maternal UTI/cystitis/pyelonephritis Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping | RR 1.02 [0.65, 1.59] | 8 studies · 4001 participants | Moderate Downgraded: imprecision |
Maternal respiratory infection (pneumonia) Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping | RR 2.3 [0.34, 15.45] | 2 studies · 1158 participants | Low Downgraded: imprecision |
Neonatal sepsis Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping | RR 0.76 [0.51, 1.13] | 5 studies · 2907 participants | Moderate Downgraded: imprecision |
Neonatal ICU admission Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping | RR 0.91 [0.74, 1.13] | 6 studies · 3708 participants | High |