Findings

What do systematic reviews say?

398 questions · 434 findings · 166 reviews

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No studies found 95 · 21.9%GRADE not reported 31 · 7.1%Very low 91 · 21%Low 110 · 25.3%Moderate 78 · 18%High 29 · 6.7%

Prophylactic platelet transfusions with low‐dose schedule vs prophylactic platelet transfusions with standard‐dose schedule

Mortality from all causes up to 30 days from study entry · People with a haematological disorder

Prophylactic platelet transfusions with low‐dose schedule showed no clear difference in mortality from all causes up to 30 days from study entry compared with prophylactic platelet transfusions with standard‐dose schedule (low certainty).

1 finding from 1 review

Different doses of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders… 2015 · Cochrane Headline outcomes only
RR 2.04 [0.7, 5.93]
3 studies · 1070 participants
Low

Intervention not reported

Mortality · adults following hip fracture surgery

The intervention showed no clear difference in mortality (moderate certainty).

1 finding from 1 review

Interventions for improving mobility after hip fracture surgery in adults 2022 · Cochrane Headline outcomes only
RR 1.01 [0.49, 2.06]
8 studies · 737 participants
Moderate

Intervention not reported

Mortality · adults following hip fracture surgery

The intervention showed no clear difference in mortality (low certainty).

1 finding from 1 review

Interventions for improving mobility after hip fracture surgery in adults 2022 · Cochrane Headline outcomes only
RR 1.06 [0.48, 2.3]
6 studies · 489 participants
Low

Drain use vs No drain

All‐cause mortality · people undergoing elective pancreatic resections

Drain use showed no clear difference in mortality compared with no drain use following pancreatic surgery (low certainty).

2 findings from 1 review

Prophylactic abdominal drainage for pancreatic surgery 2021 · Cochrane Headline outcomes only
RR 0.78 [0.31, 1.99]
4 studies · 1055 participants
Low
Prophylactic abdominal drainage for pancreatic surgery 2021 · Cochrane Headline outcomes only
RR 0.23 [0.06, 0.9]
2 studies · 478 participants
Low

Early vs late drain removal following pancreatic surgery

All‐cause mortality · people undergoing elective pancreatic resections

It is very uncertain whether early changes mortality compared with late drain removal following pancreatic surgery (very low certainty).

2 findings from 1 review

Prophylactic abdominal drainage for pancreatic surgery 2021 · Cochrane Headline outcomes only
RR 0.99 [0.06, 15.45]
3 studies · 399 participants
Very low
Prophylactic abdominal drainage for pancreatic surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Active drain vs passive drain

All‐cause mortality · people undergoing elective pancreatic resections

It is very uncertain whether active drain changes mortality compared with passive drain following pancreatic surgery (very low certainty).

2 findings from 1 review

Prophylactic abdominal drainage for pancreatic surgery 2021 · Cochrane Headline outcomes only
RR 1.23 [0.3, 5.06]
2 studies · 382 participants
Very low
Prophylactic abdominal drainage for pancreatic surgery 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Targeted individualized vs standard non‐individualized fortification

All‐cause mortality · promoting growth and development in very low birth weight infants receiving human milk

The review found no eligible studies for this question.

1 finding from 1 review

Individualized versus standard diet fortification for growth and development in preterm infants receiving human milk 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Adjustable individualized fortification vs standard non‐individualized fortification

All‐cause mortality · promoting growth and development in very low birth weight infants receiving human milk

The review found no eligible studies for this question.

1 finding from 1 review

Individualized versus standard diet fortification for growth and development in preterm infants receiving human milk 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Targeted individualized fortification vs adjustable individualized fortification

All‐cause mortality · promoting growth and development in very low birth weight infants receiving human milk

The review found no eligible studies for this question.

1 finding from 1 review

Individualized versus standard diet fortification for growth and development in preterm infants receiving human milk 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Targeted or adjustable individualized fortification vs standard non‐individualized fortification

All‐cause mortality · promoting growth and development in very low birth weight infants receiving human milk

The review found no eligible studies for this question.

1 finding from 1 review

Individualized versus standard diet fortification for growth and development in preterm infants receiving human milk 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

ASA + high‐dose LMWH vs ASA + low‐dose LMWH or UFH

All‐cause mortality · people with antiphospholipid antibodies and no history of thrombosis

The review found no eligible studies for this question.

1 finding from 1 review

Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

High vs non‐high (medium or low) dose regimen

All‐cause mortality · patients with acute peptic ulcer bleeding

High showed no clear difference in mortality compared with non‐high (medium or low) dose regimen (low certainty).

1 finding from 1 review

Comparison of different regimens of proton pump inhibitors for acute peptic ulcer bleeding 2013 · Cochrane Headline outcomes only
RR 0.85 [0.47, 1.54]
12 studies · 1667 participants
Low

Standard‐protein formula vs low‐protein formula

All‐cause mortality · healthy, full‐term (37 to 42 weeks), formula‐fed infants

The review found no eligible studies for this question.

1 finding from 1 review

Higher versus lower protein intake in formula‐fed term infants 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (long term)

All‐cause mortality · people who underwent a lower limb revascularisation

The review found no eligible studies for this question.

1 finding from 1 review

Duplex ultrasound for surveillance of lower limb revascularisation 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (short term)

All‐cause mortality · people who underwent a lower limb revascularisation

Duplex ultrasound plus pulse palpation and arterial pressure index… showed no clear difference in all‐cause mortality compared with pulse palpation plus arterial pressure index (ABI or TBI) (short term) (low certainty).

1 finding from 1 review

Duplex ultrasound for surveillance of lower limb revascularisation 2023 · Cochrane Headline outcomes only
RR 1.11 [0.7, 1.74]
1 study · 594 participants
Low

Effects of high‐ vs low‐added sugar consumption

All‐cause mortality · Adults without diabetes or CVD

The review found no eligible studies for this question.

1 finding from 1 review

High versus low‐added sugar consumption for the primary prevention of cardiovascular disease 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

High vs low blood pressure target

All‐cause mortality · adults undergoing cardiac surgery with cardiopulmonary bypass

It is very uncertain whether high changes all‐cause mortality compared with low blood pressure target (very low certainty).

1 finding from 1 review

High versus low blood pressure targets for cardiac surgery while on cardiopulmonary bypass 2022 · Cochrane Headline outcomes only
RR 1.33 [0.3, 5.9]
3 studies · 737 participants
Very low

Milrinone vs dobutamine

All‐cause mortality · adults with low cardiac output syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Inotropic agents and vasodilator strategies for the treatment of cardiogenic shock or low cardiac output syndrome 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Enoximone vs piroximone

All‐cause mortality · adults with low cardiac output syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Inotropic agents and vasodilator strategies for the treatment of cardiogenic shock or low cardiac output syndrome 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Enoximone vs epinephrine‐nitroglycerine

All‐cause mortality · adults with low cardiac output syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Inotropic agents and vasodilator strategies for the treatment of cardiogenic shock or low cardiac output syndrome 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found