What do systematic reviews say?

ZUCLOPENTHIXOL ACETATE vs placebo

The review found no eligible studies for this question.

• Zuclopenthixol versus placebo for schizophrenia 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

ZUCLOPENTHIXOL DECANOATE vs placebo

The review found no eligible studies for this question.

• Zuclopenthixol versus placebo for schizophrenia 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

BRIEF CBT vs STANDARD DURATION CBT

• Cognitive behavioural therapy (brief versus standard duration) for schizophrenia 2015 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

CHLORPROMAZINE vs placebo

CHLORPROMAZINE may leads to lower leaving the study early compared with PLACEBO (low certainty).

• Chlorpromazine versus placebo for schizophrenia 2014 · Cochrane Headline outcomes only
  RR 0.64 [0.53, 0.78]
  27 studies · 1831 participants
  Low

COMPARISON 1. ARIPIPRAZOLE vs QUETIAPINE

It is very uncertain whether COMPARISON 2. ARIPIPRAZOLE changes leaving the study early compared with QUETIAPINE (very low certainty).

• Aripiprazole versus other atypical antipsychotics for schizophrenia 2014 · Cochrane Headline outcomes only
  RR 0.8 [0.22, 2.87]
  2 studies · 168 participants
  Very low

COMPARISON 1. ARIPIPRAZOLE vs RISPERIDONE

It is very uncertain whether COMPARISON 3. ARIPIPRAZOLE changes leaving the study early compared with RISPERIDONE (very low certainty).

• Aripiprazole versus other atypical antipsychotics for schizophrenia 2014 · Cochrane Headline outcomes only
  RR 1.02 [0.79, 1.32]
  12 studies · 1239 participants
  Very low

COMPARISON 1. ARIPIPRAZOLE vs ZIPRASIDONE

It is very uncertain whether COMPARISON 4. ARIPIPRAZOLE changes leaving the study early compared with ZIPRASIDONE (very low certainty).

• Aripiprazole versus other atypical antipsychotics for schizophrenia 2014 · Cochrane Headline outcomes only
  RR 0.94 [0.66, 1.34]
  2 studies · 316 participants
  Very low

COMPARISON 1. ARIPIPRAZOLE vs OLANZAPINE

COMPARISON 5. ARIPIPRAZOLE may leads to higher leaving the study early compared with OLANZAPINE (low certainty).

• Aripiprazole versus other atypical antipsychotics for schizophrenia 2014 · Cochrane Headline outcomes only
  RR 1.15 [1.05, 1.25]
  9 studies · 2331 participants
  Low

Health education vs HEALTH EMPOWERMENT EDUCATION

HEALTH EDUCATION showed no clear difference in leaving the study early compared with HEALTH EMPOWERMENT EDUCATION (low certainty).

• General physical health advice for people with serious mental illness 2014 · Cochrane Headline outcomes only
  RR 0.56 [0.26, 1.19]
  1 study · 78 participants
  Low

HEALTHY LIVING STUDY CIRCLE vs AESTHETIC STUDY CIRCLE

HEALTHY LIVING STUDY CIRCLE led to lower leaving the study early compared with AESTHETIC STUDY CIRCLE; GRADE not reported.

• General physical health advice for people with serious mental illness 2014 · Cochrane Headline outcomes only
  RR 0 [0, 0]
  0 studies · 0 participants
  GRADE not reported

PHYSICAL HEALTH ADVICE vs usual care

It is very uncertain whether PHYSICAL HEALTH ADVICE changes leaving the study early compared with STANDARD CARE (very low certainty).

• General physical health advice for people with serious mental illness 2014 · Cochrane Headline outcomes only
  RR 1.11 [0.92, 1.35]
  6 studies · 964 participants
  Very low

HALOPERIDOL vs placebo

HALOPERIDOL showed no clear difference in leaving the study early compared with PLACEBO (moderate certainty).

• Haloperidol versus placebo for schizophrenia 2013 · Cochrane Headline outcomes only
  RR 0.54 [0.29, 1]
  8 studies · 304 participants
  Moderate

Life skills programme vs usual care

It is very uncertain whether life skills programme changes leaving the study early compared with standard care (very low certainty).

• Life skills programmes for chronic mental illnesses 2012 · Cochrane Headline outcomes only
  RR 1.16 [0.4, 3.36]
  5 studies · 345 participants
  Very low

SWITCHING ANTIPSYCHOTIC: TO QUETIAPINE vs MAINTENANCE RISPERIDONE

It is very uncertain whether SWITCHING ANTIPSYCHOTIC: TO QUETIAPINE changes leaving the study early compared with MAINTENANCE RISPERIDONE (very low certainty).

• Management of sexual dysfunction due to antipsychotic drug therapy 2012 · Cochrane Headline outcomes only
  RR 2.2 [0.45, 10.74]
  1 study · 42 participants
  Very low

SWITCHING ANTIPSYCHOTIC: TO OLANZAPINE vs MAINTENANCE RISPERIDONE/FGA

It is very uncertain whether SWITCHING ANTIPSYCHOTIC: TO OLANZAPINE changes leaving the study early compared with MAINTENANCE RISPERIDONE/FGA (very low certainty).

• Management of sexual dysfunction due to antipsychotic drug therapy 2012 · Cochrane Headline outcomes only
  RR 2.25 [0.79, 6.43]
  1 study · 54 participants
  Very low

Sildenafil vs placebo

It is very uncertain whether ADJUNCTIVE TREATMENT ‐ SPECIFIC: SILDENAFIL changes leaving the study early compared with PLACEBO (very low certainty).

• Management of sexual dysfunction due to antipsychotic drug therapy 2012 · Cochrane Headline outcomes only
  RR 0.33 [0.01, 7.62]
  1 study · 32 participants
  Very low

ADJUNCTIVE TREATMENT ‐ NON‐SPECIFIC: SELEGILINE vs placebo

• Management of sexual dysfunction due to antipsychotic drug therapy 2012 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 10 participants
  Very low

CHLORPROMAZINE vs haloperidol

It is very uncertain whether CHLORPROMAZINE changes leaving the study early compared with HALOPERIDOL (very low certainty).

• Chlorpromazine for psychosis induced aggression or agitation 2010 · Cochrane Headline outcomes only
  RR 2 [0.2, 19.78]
  1 study · 30 participants
  Very low

Summary of findings 1. INTERCESSORY PRAYER (CONTEMPORANEOUS ) vs usual care

Summary of findings 1. INTERCESSORY PRAYER (CONTEMPORANEOUS ) showed no clear difference in leaving the study early compared with STANDARD CARE (moderate certainty).

• Intercessory prayer for the alleviation of ill health 2009 · Cochrane Headline outcomes only
  RR 0.75 [0.43, 1.31]
  6 studies · 3446 participants
  Moderate

INTERMITTENT (CRISIS INTERVENTION) vs MAINTENANCE THERAPY

It is very uncertain whether INTERMITTENT (CRISIS INTERVENTION) changes leaving the study early/ loss to compared with MAINTENANCE THERAPY (very low certainty).

• Intermittent drug techniques for schizophrenia 2013 · Cochrane Headline outcomes only
  RR 1.57 [1.23, 2]
  1 study · 237 participants
  Very low