Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

42 questions · 43 findings · 29 reviews

No studies found 2 · 4.7%GRADE not reported 0 · 0%Very low 15 · 34.9%Low 20 · 46.5%Moderate 6 · 14%High 0 · 0%

IVF vs expectant management

Clinical pregnancy rate · women with unexplained subfertility

It is very uncertain whether IVF changes clinical pregnancy rate per woman randomised compared with expectant management (very low certainty).

1 finding from 1 review

IVF vs unstimulated IUI

Clinical pregnancy rate · women with unexplained subfertility

It is very uncertain whether IVF changes clinical pregnancy rate per woman randomised compared with unstimulated IUI (very low certainty).

1 finding from 1 review

Any glucocorticoid vs no glucocorticoids or placebo

Clinical pregnancy rate per couple – subgroup IVF · assisted reproduction technology cycles

It is very uncertain whether glucocorticoids changes clinical pregnancy rate per couple – subgroup IVF compared with no glucocorticoids or placebo (very low certainty).

1 finding from 1 review

G‐CSF vs no treatment or placebo

Clinical pregnancy rate ‐ unselected or unstated IVF number · Subfertile women undergoing assisted reproduction

G‐CSF showed no clear difference in clinical pregnancy rate ‐ unselected or unstated IVF number compared with no treatment or placebo (low certainty).

1 finding from 1 review

ART with seminal plasma vs standard ART (IVF, ICSI, and frozen embryo transfer)

Clinical pregnancy · Women undergoing ART (IVF, ICSI, or frozen embryo transfer)

It is very uncertain whether ART with seminal plasma changes clinical pregnancy compared with standard ART (IVF, ICSI, and frozen embryo transfer) (very low certainty).

1 finding from 1 review

Day 3 vs Day 2 embryo transfer following IVF or ICSI

Clinical pregnancy rate · Women undergoing in vitro fertilisation or intracytoplasmic sperm injection

It is very uncertain whether day 3 changes clinical pregnancy rate per woman compared with day 2 embryo transfer following IVF or ICSI (very low certainty).

1 finding from 1 review

Summary of findings table ‐ ICSI vs c‐IVF

Clinical pregnancy · : Couples with males presenting normal total sperm count and motility were included in this review.

Summary of findings table ‐ ICSI showed no clear difference in clinical Pregnancy compared with c‐IVF (low certainty).

1 finding from 1 review

Transvaginal aspiration of hydrosalpingeal fluid vs laparoscopic salpingectomy

Clinical pregnancy rate · tubal disease in women due to undergo in vitro fertilisation

It is very uncertain whether transvaginal aspiration of hydrosalpingeal fluid changes clinical pregnancy rate compared with laparoscopic salpingectomy (very low certainty).

1 finding from 1 review

Repeated single embryo transfer (mixed policies) vs multiple embryo transfer

Clinical pregnancy rate · transfer following in vitro fertilisation or intracytoplasmic sperm injection

Repeated single embryo transfer (mixed policies) showed no clear difference in clinical pregnancy rate compared with multiple embryo transfer (low certainty).

1 finding from 1 review

Long‐term GnRH agonist therapy vs no additional therapy

Clinical pregnancy rate · patients with endometriosis prior to standard IVF/ICSI

It is very uncertain whether long‐term GnRH agonist therapy changes clinical pregnancy rate compared with no additional therapy (very low certainty).

1 finding from 1 review

Monitoring ovarian stimulation by transvaginal ultrasound (TVUS) only vs monitoring with TVUS plus serum estradiol

Clinical pregnancy · Women undergoing ovarian stimulation with gonadotrophins in IVF and ICSI procedures

Monitoring ovarian stimulation by transvaginal ultrasound (TVUS) only showed no clear difference in clinical pregnancy per woman compared with monitoring with TVUS plus serum estradiol (low certainty).

1 finding from 1 review