Cochrane · systematic review · CD011809
Application of seminal plasma to female genital tract prior to embryo transfer in assisted reproductive technology cycles (IVF, ICSI and frozen embryo transfer)
Ata, B, Abou‐Setta, AM, Seyhan, A, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
Gynaecology and FertilityAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 2 · 28.6%Low 4 · 57.1%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
ART with seminal plasma compared to standard ART (IVF, ICSI, and frozen embryo transfer)
Population: Women undergoing ART (IVF, ICSI, or frozen embryo transfer)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth ART with seminal plasma vs standard ART (IVF, ICSI, and frozen embryo transfer) | RR 1.1 [0.86, 1.43] | 3 studies · 948 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Miscarriage ART with seminal plasma vs standard ART (IVF, ICSI, and frozen embryo transfer) | RR 1.01 [0.57, 1.79] | 4 studies · 1209 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Live birth or ongoing pregnancy ART with seminal plasma vs standard ART (IVF, ICSI, and frozen embryo transfer) | RR 1.19 [0.95, 1.49] | 4 studies · 1178 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Clinical pregnancy ART with seminal plasma vs standard ART (IVF, ICSI, and frozen embryo transfer) | RR 1.15 [1.01, 1.31] | 10 studies · 2768 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Multiple pregnancy ART with seminal plasma vs standard ART (IVF, ICSI, and frozen embryo transfer) | RR 1.11 [0.76, 1.64] | 5 studies · 1642 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Ectopic pregnancy ART with seminal plasma vs standard ART (IVF, ICSI, and frozen embryo transfer) | RR 1.59 [0.2, 12.78] | 5 studies · 1521 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Adverse events, including infectious complications ART with seminal plasma vs standard ART (IVF, ICSI, and frozen embryo transfer) | no estimate extracted | NR | No studies |