Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

10 questions · 10 findings · 7 reviews

No studies found 1 · 10%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 30%Moderate 2 · 20%High 4 · 40%

Lung cancer screening with chest radiography +/‐ sputum cytology vs less intense screening

All‐cause mortality ‐ More frequent chest x‐ray screening versus less frequent screening · Patients with lung cancer

Lung cancer screening with chest radiography +/‐ sputum cytology showed no clear difference in all‐cause mortality ‐ More frequent chest x‐ray screening versus… compared with less intense screening (low certainty).

1 finding from 1 review

Systematic screening vs no/opportunistic screening

All‐cause mortality · general population including those at moderate to high risk of CVD, mean age between 30 and 75

Systematic screening showed no clear difference in all‐cause mortality compared with no/opportunistic screening (low certainty).

1 finding from 1 review

Low‐dose computed tomography (LDCT) screening vs no LDCT screening

All‐cause mortality ‐ planned time points · healthy adults

Low‐dose computed tomography (LDCT) screening probably leads to lower all‐cause mortality ‐ planned time points compared with no LDCT screening (moderate certainty).

1 finding from 1 review

Lung cancer screening with chest radiography +/‐ sputum cytology vs less intense screening

All‐cause mortality ‐ Annual chest x‐ray plus 4‐monthly cytology versus annual x‐ray alone · Patients with lung cancer

Lung cancer screening with chest radiography +/‐ sputum cytology showed no clear difference in all‐cause mortality ‐ Annual chest x‐ray plus 4‐monthly cytology… compared with less intense screening (high certainty).

1 finding from 1 review

Intervention not reported

All‐cause mortality · adult male patients

The intervention showed no clear difference in all‐cause mortality (moderate certainty).

1 finding from 1 review

Intervention not reported

All‐cause mortality Median · individuals without known diabetes mellitus but at high risk for the condition

The intervention showed no clear difference in all‐cause mortality Median (low certainty).

1 finding from 1 review