Cochrane · systematic review · CD004720

Screening for prostate cancer

Ilic, D, Neuberger, MM, Djulbegovic, M, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library

UrologyAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
5
No studies
1
Included studies
NR
No studies 1 · 16.7%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 33.3%Moderate 3 · 50%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Screening for prostate cancer

Population: adult male patients
6 questions
OutcomeEffectEvidenceStatus / GRADE
Outcomes1
no estimate extractedNRNo studies
All‐cause mortality
RR 1 [0.96, 1.03]4 studies · 294856 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Prostate cancer‐specific mortality
RR 1 [0.86, 1.17]5 studies · 341342 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency
Prostate cancer diagnosis
RR 1.3 [1.02, 1.65]4 studies · 294856 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Tumour stage (localised T1‐T2, N0, M0)
RR 1.79 [1.19, 2.7]3 studies · 247954 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Tumour stage (advanced T3‐4, N1, M1)
RR 0.8 [0.73, 0.87]3 studies · 247954 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency