Cochrane · systematic review · CD009259
Flexible sigmoidoscopy versus faecal occult blood testing for colorectal cancer screening in asymptomatic individuals
Holme, Ø, Bretthauer, M, Fretheim, A, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
ColorectalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 16.7%High 5 · 83.3%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Screening for colorectal cancer with flexible sigmoidoscopy or faecal occult blood test
Population: Asymptomatic individuals
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
CRC Mortality ‐ Flexible sigmoidoscopy | RR 0 [0.65, 0.79] | 5 studies · 414744 participants | High |
CRC Mortality ‐ Faecal occult blood testing | RR 0 [0.8, 0.92] | 4 studies · 329642 participants | High |
CRC incidence ‐ Flexible sigmoidoscopy | RR 0 [0.73, 0.9] | 5 studies · 414744 participants | Moderate Downgraded: inconsistency |
CRC incidence ‐ Faecal occult blood testing | RR 0 | 4 studies · 329536 participants | High |
All‐cause Mortality ‐ Flexible sigmoidoscopy | RR 0 [0.95, 1.01] | 4 studies · 364827 participants | High |
All‐cause Mortality ‐ Faecal occult blood testing | RR 1 | 4 studies · 329642 participants | High |