Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

39 questions · 39 findings · 22 reviews · Headline outcomes only

No studies found 19 · 48.7%GRADE not reported 1 · 2.6%Very low 4 · 10.3%Low 10 · 25.6%Moderate 3 · 7.7%High 2 · 5.1%

Zinc vs no zinc supplementation

Mortality due to all‐cause diarrhea · otherwise healthy children aged 6 months to 12 years of age

Zinc supplementation showed no clear difference in mortality due to all‐cause diarrhea compared with no zinc supplementation (moderate certainty).

1 finding from 1 review

Surgical portosystemic shunts vs transjugular intrahepatic portosystemic shunt (TIPS)

All‐cause mortality at 5 years · people with cirrhotic portal hypertension

It is very uncertain whether surgical portosystemic shunts changes all‐cause mortality at 5 years compared with transjugular intrahepatic portosystemic shunt (TIPS) (very low certainty).

1 finding from 1 review

Antihypertensive drug therapy vs placebo or no treatment

All‐cause mortality · adults (18 years of age or older) with hypertension‐induced left ventricular hypertrophy

It is very uncertain whether antihypertensive therapy changes all‐cause mortality compared with placebo or no treatment (very low certainty).

1 finding from 1 review