Cochrane · systematic review · CD008824
Vitamin D supplementation for preventing infections in children under five years of age
Yakoob, MY, Salam, RA, Khan, FR, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
Infectious DiseasesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 4 · 44.4%Very low 1 · 11.1%Low 3 · 33.3%Moderate 1 · 11.1%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Vitamin D versus control for preventing infections in children under five years of age
Population: children under five years of age
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality Vitamin D vs control | no estimate extracted | 1 study · 3046 participants | Low Downgraded: imprecision, indirectness |
Cause‐specific mortality Vitamin D vs control | no estimate extracted | 1 study · 3046 participants | Low Downgraded: imprecision, indirectness |
Incidence rate radiologically confirmed first or only episode of pneumonia Vitamin D vs control | no estimate extracted | 2 studies · 3134 participants | Moderate Downgraded: imprecision, indirectness |
Any hospital admission Vitamin D vs control | no estimate extracted | 1 study · 88 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
TB cases Vitamin D vs control | no estimate extracted | 0 studies · 0 participants | Ungraded |
Diarrhoea cases Vitamin D vs control | no estimate extracted | 2 studies · 7 participants | Ungraded |
Malaria cases Vitamin D vs control | no estimate extracted | 0 studies · 0 participants | Ungraded |
Febrile illness Vitamin D vs control | no estimate extracted | 0 studies · 0 participants | Ungraded |
Mean serum vitamin D concentrations Vitamin D vs control | no estimate extracted | 4 studies · 266 participants | Low Downgraded: imprecision, indirectness |