Cochrane · systematic review · CD001023

Surgical portosystemic shunts versus transjugular intrahepatic portosystemic shunt for variceal haemorrhage in people with cirrhosis

Brand, M, Prodehl, L, Ede, CJ · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

Hepato-BiliaryAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 14.3%Very low 6 · 85.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Surgical portosystemic shunts compared to transjugular intrahepatic portosystemic shunt (TIPS) for variceal haemorrhage

Population: people with cirrhotic portal hypertension
7 questions
OutcomeEffectEvidenceStatus / GRADE
All‐cause mortality at 30 days
Surgical portosystemic shunts vs transjugular intrahepatic portosystemic shunt (TIPS)
RR 0.94 [0.44, 1.99]4 studies · 496 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
All‐cause mortality at 5 years
Surgical portosystemic shunts vs transjugular intrahepatic portosystemic shunt (TIPS)
RR 0.61 [0.42, 0.9]4 studies · 496 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Number of participants with Variceal rebleeding episodes at 30 days
Surgical portosystemic shunts vs transjugular intrahepatic portosystemic shunt (TIPS)
RR 0.18 [0.07, 0.49]4 studies · 496 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Number of participants with reintervention at 5 years
Surgical portosystemic shunts vs transjugular intrahepatic portosystemic shunt (TIPS)
RR 0.13 [0.06, 0.28]4 studies · 496 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Irreversible shunt occlusion at 5 years
Surgical portosystemic shunts vs transjugular intrahepatic portosystemic shunt (TIPS)
RR 0.14 [0.04, 0.51]4 studies · 496 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Number of participants with encephalopathy at 5 years
Surgical portosystemic shunts vs transjugular intrahepatic portosystemic shunt (TIPS)
RR 0.56 [0.27, 1.16]4 studies · 496 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Health‐related quality of life
Surgical portosystemic shunts vs transjugular intrahepatic portosystemic shunt (TIPS)
no estimate extracted2 studies · 210 participantsUngraded