Cochrane · systematic review · CD011283

Processed electroencephalogram and evoked potential techniques for amelioration of postoperative delirium and cognitive dysfunction following non‐cardiac and non‐neurosurgical procedures in adults

Punjasawadwong, Y, Chau‐in, W, Laopaiboon, M, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 40%Moderate 3 · 60%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Processed EEG or EP indices guided anaesthesia for patients undergoing general anaesthesia for surgical procedures

Population: adults aged 18 years or over undergoing general anaesthesia for non‐cardiac or non‐neurosurgical elective operations
5 questions
OutcomeEffectEvidenceStatus / GRADE
Postoperative delirium (POD) within 7 days (As assessed by any method such as the Mini‐Mental State Examination (MMSE) and Confusion Assessment Method (CAM) in the first week after operation)
RR 0.71 [0.59, 0.85]3 studies · 2197 participantsModerate
Downgraded: risk of bias
Postoperative cognitive dysfunction (POCD) (As determined by any method of assessing POCD including a battery of neuropsychological tests according to the criteria described by the International Study of Postoperative Cognitive Dysfunction (ISPOCD))
RR 0.84 [0.69, 1.02]3 studies · 1989 participantsModerate
Downgraded: risk of bias
All‐cause mortality
RR 1.01 [0.62, 1.64]1 study · 1155 participantsLow
Downgraded: risk of bias, imprecision
Any postoperative complication
RR 0.51 [0.37, 0.71]1 study · 902 participantsModerate
Downgraded: risk of bias
Postoperative length of stay (days)
no estimate extracted1 study · 1155 participantsLow
Downgraded: risk of bias, imprecision