Cochrane · systematic review · CD008959

Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years of age

Suchdev, PS, Jefferds, MED, Ota, E, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
7
No studies
5
Included studies
NR
No studies 5 · 41.7%Ungraded 0 · 0%Very low 1 · 8.3%Low 2 · 16.7%Moderate 3 · 25%High 1 · 8.3%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

Home (point‐of‐use) fortification of foods with multiple micronutrient powders versus no intervention or placebo in children under two years of age

Population: children 6 to 23 months of age
6 questions
OutcomeEffectEvidenceStatus / GRADE
Anaemia (haemoglobin values lower than 110 g/L)
Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs no intervention or placebo
RR 0.82 [0.76, 0.9]16 studies · 9927 participantsModerate
Downgraded: inconsistency
Iron deficiency (as defined by trialists)
Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs no intervention or placebo
RR 0.47 [0.39, 0.56]7 studies · 1634 participantsHigh
Haemoglobin concentration (g/L)
Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs no intervention or placebo
no estimate extracted20 studies · 10509 participantsLow
Downgraded: risk of bias, inconsistency
Iron status (ferritin concentrations in μg/L)
Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs no intervention or placebo
no estimate extracted7 studies · 2612 participantsModerate
Downgraded: inconsistency
Weight‐for‐age (z scores)
Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs no intervention or placebo
no estimate extracted10 studies · 9287 participantsModerate
Downgraded: risk of bias
All‐cause mortality
Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs no intervention or placebo
no estimate extractedNRNo studies

Home (point‐of‐use) fortification of foods with multiple micronutrient powders versus an iron‐only supplement in children under two years of age

Population: children 6 to 23 months of age
6 questions
OutcomeEffectEvidenceStatus / GRADE
Anaemia (haemoglobin values lower than 110 g/L)
Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs an iron‐only supplement
RR 0.89 [0.58, 1.39]1 study · 145 participantsLow
Downgraded: imprecision
Iron deficiency (as defined by trialists)
Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs an iron‐only supplement
no estimate extractedNRNo studies
Haemoglobin concentration (g/L)
Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs an iron‐only supplement
no estimate extracted2 studies · 278 participantsVery low
Downgraded: imprecision, inconsistency
Iron status (as defined by trialists)
Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs an iron‐only supplement
no estimate extractedNRNo studies
Weight‐for‐age (z scores)
Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs an iron‐only supplement
no estimate extractedNRNo studies
All‐cause mortality
Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs an iron‐only supplement
no estimate extractedNRNo studies