Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

1,041 questions · 1,056 findings · 283 reviews

No studies found 346 · 32.8%GRADE not reported 111 · 10.5%Very low 326 · 30.9%Low 195 · 18.5%Moderate 66 · 6.3%High 12 · 1.1%

Pharmacological interventions vs placebo

Gastrointestinal adverse events · people with depression after stroke

It is very uncertain whether pharmacological interventions changes adverse events: all ‐ gastrointestinal effects (e.g. constipation,… compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

Adverse effects (central nervous system) · people with depression after stroke

It is very uncertain whether pharmacological interventions changes adverse events: all ‐ central nervous system events (e.g. confusion,… compared with placebo (very low certainty).

1 finding from 1 review

Lay health worker‐ vs enhanced usual care

Adverse events ‐ death in past 12 months (RR > 1 denotes higher risk of death) · adult patients with alcohol dependence

It is very uncertain whether lay health worker‐led interventions changes adverse events ‐ death in past 12 months (RR > 1 denotes higher risk… compared with enhanced usual care (very low certainty).

1 finding from 1 review

Assistive technology for vision improvement interventions vs usual care or attention control

Adverse events Falls while switching glasses · Older people living in the community

Assistive technology for vision improvement interventions showed no clear difference in adverse events Falls while switching glasses compared with usual care or attention control (low certainty).

1 finding from 1 review

Antidepressants vs placebo

Adverse events: death ‐ at end of treatment (Analysis 1.14) · people with stroke

It is very uncertain whether pharmacological interventions (antidepressants) changes adverse events: death ‐ at end of treatment Analysis 1.12 compared with placebo (very low certainty).

1 finding from 1 review

Psychological interventions vs usual care

Treatment‐related adverse events Anxiety: GAD‐7 (Spitzer 2006) · children, adolescents or adults with CF

Summary of findings: psychological interventions showed no clear difference in treatment‐related adverse events Anxiety: GAD‐7 (Spitzer 2006) compared with usual care (low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Adverse events RR < 1 indicates lower risk of adverse events · adults with common mental disorders

Lay health worker‐led psychological interventions may leads to lower adverse events RR < 1 indicates lower risk of adverse events compared with usual care (low certainty).

1 finding from 1 review

Psychological interventions vs usual care

Treatment‐related adverse events Depression PHQ‐8 (Kroenke 2009) · children, adolescents or adults with CF

Summary of findings: psychological interventions showed no clear difference in treatment‐related adverse events Depression PHQ‐8 (Kroenke 2009) compared with usual care (low certainty).

1 finding from 1 review

Primary health professional‐led psychological interventions vs usual care or no treatment

Adverse events (RR > 1 denotes greater risk of harm) · adults with post‐traumatic stress or common mental disorders

It is very uncertain whether primary health professional‐led psychological interventions changes adverse events (RR > 1 denotes greater risk of harm) compared with usual or no care (very low certainty).

1 finding from 1 review