Cochrane · systematic review · CD013766
Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis
Dawson, S, Girling, C-J, Cowap, L, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
Cystic Fibrosis and Genetic DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
10
No studies
2
Included studies
NR
No studies 2 · 16.7%Ungraded 0 · 0%Very low 4 · 33.3%Low 3 · 25%Moderate 3 · 25%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings: psychological interventions compared with usual care
Population: children, adolescents or adults with CF
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Adherence to inhaled therapies: % of prescribed inhaled therapies taken Summary of findings: psychological interventions vs usual care | MD 9.5 [8.6, 10.4] | 1 study · 588 participants | Moderate Downgraded: risk of bias, indirectness |
Treatment‐related adverse events Anxiety: GAD‐7 (Spitzer 2006) Summary of findings: psychological interventions vs usual care | MD 0.3 | 1 study · 535 participants | Low Downgraded: risk of bias, indirectness |
Treatment‐related adverse events Depression PHQ‐8 (Kroenke 2009) Summary of findings: psychological interventions vs usual care | no estimate extracted | 1 study · 534 participants | Low Downgraded: risk of bias, indirectness |
QoL CFQ‐R (Quittner 2009) Summary of findings: psychological interventions vs usual care | MD 3.9 [1.2, 6.6] | 1 study · 539 participants | Low Downgraded: risk of bias, indirectness |
Lung function FEV1 % predicted Summary of findings: psychological interventions vs usual care | MD 1.4 | 1 study · 556 participants | Moderate Downgraded: risk of bias, indirectness |
Pulmonary exacerbations Summary of findings: psychological interventions vs usual care | no estimate extracted | 1 study · 607 participants | Moderate Downgraded: risk of bias, indirectness |
Summary of findings: psychological interventions compared with an active comparator
Population: adults (aged 16 years and over) with CF
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Adherence to inhaled therapies cMPR Summary of findings: psychological interventions vs an active comparator | no estimate extracted | 1 study · 95 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Treatment‐related adverse events Anxiety Summary of findings: psychological interventions vs an active comparator | no estimate extracted | NR | No studies |
Treatment‐related adverse events Depression Summary of findings: psychological interventions vs an active comparator | no estimate extracted | NR | No studies |
QoL CFQ‐R (Quittner 2009) Summary of findings: psychological interventions vs an active comparator | no estimate extracted | 1 study · 95 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Lung function FEV1 % predicted Summary of findings: psychological interventions vs an active comparator | no estimate extracted | 1 study · 125 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Pulmonary exacerbations Summary of findings: psychological interventions vs an active comparator | no estimate extracted | 1 study · 128 participants | Very low Downgraded: risk of bias, imprecision, indirectness |