Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

404 questions · 409 findings · 122 reviews

No studies found 77 · 18.8%GRADE not reported 31 · 7.6%Very low 142 · 34.7%Low 83 · 20.3%Moderate 63 · 15.4%High 13 · 3.2%

Summary of findings: cycled vs culture‐based antibiotic therapy

Adverse events: severe adverse events (total) · children (aged 1 to 12 years) with CF and a newly isolated PA infection

Summary of findings: cycled showed no clear difference in adverse events: severe adverse events (total) compared with culture‐based antibiotic therapy (moderate certainty).

1 finding from 1 review

Summary of findings: Defibrotide vs no treatment

Frequency of adverse events ( · Children undergoing stem cell transplant with malignant and non‐malignant diseases and risk factors for hepatic veno‐occlusive disease

It is very uncertain whether summary of findings: Defibrotide changes frequency of adverse events ( compared with no treatment (very low certainty).

1 finding from 1 review

Summary of findings 2. Octenidine‐dihydrochloride (OCT) hydrogel dressings vs OCT‐free placebo hydrogel dressings

Adverse events · adults with skin graft donor sites

It is very uncertain whether summary of findings 2. Octenidine‐dihydrochloride (OCT) hydrogel… changes adverse events compared with OCT‐free placebo hydrogel dressings (very low certainty).

1 finding from 1 review