Cochrane · systematic review · CD006961
Combination antimicrobial susceptibility testing for acute exacerbations in chronic infection of Pseudomonas aeruginosa in cystic fibrosis
Smith, S, Ratjen, F, Remmington, T, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
1
No studies
6
Included studies
NR
No studies 6 · 85.7%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 14.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsSummary of findings for combination antimicrobial susceptibility testing compared with conventional treatment (separate testing) for pulmonary exacerbation due to Pseudomonas aeruginosa in people with cystic fibrosis
Population: adults and children with pulmonary exacerbation due to Pseudomonas aeruginosa
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Lung function(FEV1 or FVC L/min or % predicted) Summary of findings for combination antimicrobial susceptibility testing vs conventional treatment (separate testing) | no estimate extracted | NR | No studies |
Time to next exacerbation Summary of findings for combination antimicrobial susceptibility testing vs conventional treatment (separate testing) | no estimate extracted | 1 study · 82 participants | Moderate Downgraded: imprecision |
Quality of life Summary of findings for combination antimicrobial susceptibility testing vs conventional treatment (separate testing) | no estimate extracted | NR | No studies |
Length of hospital stay Summary of findings for combination antimicrobial susceptibility testing vs conventional treatment (separate testing) | no estimate extracted | NR | No studies |
Sputum bacterial density (CFU/mL) Summary of findings for combination antimicrobial susceptibility testing vs conventional treatment (separate testing) | no estimate extracted | NR | No studies |
Adverse events Summary of findings for combination antimicrobial susceptibility testing vs conventional treatment (separate testing) | no estimate extracted | NR | No studies |
Mortality Summary of findings for combination antimicrobial susceptibility testing vs conventional treatment (separate testing) | no estimate extracted | NR | No studies |