Question · asked by 1 review

Imiquimod vs cidofovir: Total serious adverse events

Summary of findings for imiquimod showed no clear difference in total serious adverse events compared with cidofovir (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Summary of findings for imiquimod vs cidofovir
Total serious adverse events · women with usual‐type vulval intraepithelial neoplasia
Summary of findings for imiquimod showed no clear difference in total serious adverse events compared with cidofovir (moderate certainty).
Medical and surgical interventions for the treatment of usual‐type vulval intraepithelial neoplasia (2016) · Cochrane Headline outcomes only
RR 1.26 [0.88, 1.81]1 study · 168 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Medical and surgical interventions for the treatment of usual‐type vulval intraepithelial neoplasia
2016 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.