What do systematic reviews say?

Electroacupuncture vs no treatment

• Interventions for fatigue in inflammatory bowel disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 34 participants
  Low

Zinc tape vs magnesium sulphate glycerin

The review found no eligible studies for this question.

• Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Alpha‐blockers vs placebo

Alpha blockers may leads to higher adverse events Any adverse event compared with placebo (low certainty).

• Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome 2019 · Cochrane Headline outcomes only
  RR 1.6 [1.09, 2.34]
  19 studies · 1588 participants
  Low

Summary of findings. Removable splintage vs cast

• Interventions for treating wrist fractures in children 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 87 participants
  GRADE not reported

Summary of findings. Home vs hospital‐clinic removal of casts

• Interventions for treating wrist fractures in children 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 288 participants
  GRADE not reported

Circuit class therapy vs other interventions

It is very uncertain whether circuit class therapy changes adverse events (falls) from all available trials Counts of numbers… compared with other intervention (very low certainty).

• Circuit class therapy for improving mobility after stroke 2017 · Cochrane Headline outcomes only
  RD 0.03
  8 studies · 815 participants
  Very low

Heparin vs pentasaccharide

It is very uncertain whether heparin changes adverse events (thrombocytopenia) compared with pentasaccharide (very low certainty).

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  RR 0.34 [0.01, 8.25]
  1 study · 198 participants
  Very low

Heparin started before vs after the surgical procedure

The review found no eligible studies for this question.

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Higher‐dose heparin vs standard‐dose heparin

It is very uncertain whether higher‐dose heparin changes adverse events (thrombocytopenia) compared with standard‐dose heparin (very low certainty).

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  RR 1.1 [0.07, 17.4]
  2 studies · 310 participants
  Very low

Oral ciclosporin vs azathioprine (AZA)

Oral ciclosporin may leads to higher adverse events: minor (hirsutism) compared with oral azathioprine (low certainty).

• Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes only
  RR 9.83 [1.32, 72.95]
  1 study · 89 participants
  Low

Oral ferric maltol vs IV ferric carboxymaltose

It is very uncertain whether oral ferric maltol changes serious adverse events (12 weeks) compared with IV ferric carboxymaltose (very low certainty).

• Interventions for treating iron deficiency anaemia in inflammatory bowel disease 2021 · Cochrane Headline outcomes only
  RR 2.95 [0.98, 8.91]
  1 study · 252 participants
  Very low

Medicine‐separated moxibustion combined with acupuncture vs wheat bran‐separated moxibustion combined with shallow acupuncture

• Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 102 participants
  Very low

Web‐based education vs standard book‐based education

• Interventions for the management of abdominal pain in Crohn's disease and inflammatory bowel disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  Very low

Relaxation vs WAIT LIST

The review found no eligible studies for this question.

• Interventions for the management of abdominal pain in ulcerative colitis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Stellate ganglion block vs sulphasalazine

The review found no eligible studies for this question.

• Interventions for the management of abdominal pain in ulcerative colitis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Opioids vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for painful sickle cell vaso‐occlusive crises in adults 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Opioids vs active comparators

The review found no eligible studies for this question.

• Pharmacological interventions for painful sickle cell vaso‐occlusive crises in adults 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Mesalamine vs placebo

Mesalamine showed no clear difference in withdrawals due to adverse events compared with placebo (low certainty).

• Interventions for treating collagenous colitis 2017 · Cochrane Headline outcomes only
  RR 5.92 [0.7, 49.9]
  1 study · 62 participants
  Low

Budesonide vs placebo

It is very uncertain whether budesonide changes withdrawals due to adverse events compared with placebo (very low certainty).

• Interventions for treating collagenous colitis 2017 · Cochrane Headline outcomes only
  RR 0.97 [0.43, 2.17]
  5 studies · 290 participants
  Very low

Boswellia serrata vs placebo

Boswellia serrata extract showed no clear difference in withdrawals due to adverse events compared with placebo (low certainty).

• Interventions for treating collagenous colitis 2017 · Cochrane Headline outcomes only
  RR 2.82 [0.12, 64.39]
  1 study · 31 participants
  Low