Cochrane · systematic review · CD013589

Interventions for the management of abdominal pain in ulcerative colitis

Sinopoulou, V, Gordon, M, Dovey, TM., et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
24
current version
GRADE rated
11
No studies
12
Included studies
NR
No studies 12 · 50%Ungraded 1 · 4.2%Very low 11 · 45.8%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Low FODMAPs diet compared to sham diet for the management of abdominal pain in ulcerative colitis

Population: UC patients
4 questions
OutcomeEffectEvidenceStatus / GRADE
Treatment success as defined by the authors
Low FODMAPs diet vs sham diet
no estimate extractedNRNo studies
Pain frequency (measured in days of pain on the IBS‐SSS questionnaire)
Low FODMAPs diet vs sham diet
no estimate extracted1 study · 26 participantsVery low
Downgraded: risk of bias, imprecision
Pain intensity (0‐10cm visual analogue scale)
Low FODMAPs diet vs sham diet
no estimate extracted1 study · 26 participantsVery low
Downgraded: risk of bias, imprecision
Withdrawal due to adverse events
Low FODMAPs diet vs sham diet
RR 1.851 study · 52 participantsVery low
Downgraded: risk of bias, imprecision

Relaxation training compared to wait‐list for the management of abdominal pain in ulcerative colitis

Population: UC patients
6 questions
OutcomeEffectEvidenceStatus / GRADE
Treatment success as defined by the authors
Relaxation training vs wait‐list
no estimate extractedNRNo studies
Pain frequency (end of intervention, hours between pain episodes)
Relaxation training vs wait‐list
no estimate extracted1 study · 40 participantsVery low
Downgraded: risk of bias, imprecision
Pain frequency (6 weeks after end of intervention, hours between pain episodes)
Relaxation training vs wait‐list
no estimate extracted1 study · 40 participantsVery low
Downgraded: risk of bias, imprecision
Pain intensity (end of intervention, unidentified 0‐10 scale)
Relaxation training vs wait‐list
no estimate extracted1 study · 40 participantsVery low
Downgraded: risk of bias, imprecision
Pain intensity (6 weeks after end of intervention, unidentified 0‐10 scale)
Relaxation training vs wait‐list
no estimate extracted1 study · 40 participantsVery low
Downgraded: risk of bias, imprecision
Withdrawals due to adverse events
Relaxation training vs wait‐list
no estimate extractedNRNo studies

Yoga intervention compared to no intervention for the management of abdominal pain in ulcerative colitis

Population: UC patients
6 questions
OutcomeEffectEvidenceStatus / GRADE
Treatment success as defined by the authors
Yoga intervention vs no intervention
no estimate extractedNRNo studies
Pain frequency
Yoga intervention vs no intervention
no estimate extractedNRNo studies
Pain intensity
Yoga intervention vs no intervention
no estimate extractedNRNo studies
Withdrawal due to adverse events
Yoga intervention vs no intervention
RR 0.5 [0.05, 5.22]1 study · 60 participantsVery low
Downgraded: risk of bias, imprecision
State anxiety (20‐item State Anxiety Inventory, results range between 20 and 80)
Yoga intervention vs no intervention
no estimate extracted1 study · 60 participantsVery low
Downgraded: risk of bias, imprecision
Trait anxiety (20‐item Trait Anxiety Inventory, results range between 20 and 80)
Yoga intervention vs no intervention
no estimate extracted1 study · 60 participantsVery low
Downgraded: risk of bias, imprecision

Kefir compared to no intervention for the management of abdominal pain in ulcerative colitis

Population: UC patients
4 questions
OutcomeEffectEvidenceStatus / GRADE
Treatment success as defined by the authors
Kefir vs no intervention
no estimate extractedNRNo studies
Pain frequency
Kefir vs no intervention
no estimate extractedNRNo studies
Pain intensity (measure on a 0‐3 four‐point scale)
Kefir vs no intervention
no estimate extracted1 study · 25 participantsVery low
Downgraded: risk of bias, imprecision
Withdrawals due to adverse events
Kefir vs no intervention
no estimate extracted1 study · 20 participantsUngraded

Stellate ganglion block compared to sulphasalazine for the management of abdominal pain in ulcerative colitis

Population: UC patients
4 questions
OutcomeEffectEvidenceStatus / GRADE
Treatment success as defined by the authors
Stellate ganglion block vs sulphasalazine
no estimate extractedNRNo studies
Pain frequency
Stellate ganglion block vs sulphasalazine
no estimate extractedNRNo studies
Pain intensity (measure on a 0‐3 four‐point scale)
Stellate ganglion block vs sulphasalazine
no estimate extractedNRNo studies
Withdrawals due to adverse events
Stellate ganglion block vs sulphasalazine
no estimate extractedNRNo studies