Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

891 questions · 902 findings · 317 reviews

No studies found 210 · 23.3%GRADE not reported 56 · 6.2%Very low 236 · 26.2%Low 220 · 24.4%Moderate 146 · 16.2%High 34 · 3.8%

Active cancer therapy combined with TCM vs active cancer therapy

Adverse events ‐ white blood cell descent Diagnosed by clinicians · patients with oesophageal cancer

It is very uncertain whether active cancer therapy combined with TCM changes adverse events ‐ white blood cell descent Diagnosed by clinicians compared with active cancer therapy (very low certainty).

1 finding from 1 review

Active cancer therapy combined with TCM vs active cancer therapy

Adverse events ‐ gastrointestinal reactions Diagnosed by clinicians · patients with oesophageal cancer

It is very uncertain whether active cancer therapy combined with TCM changes adverse events ‐ gastrointestinal reactions Diagnosed by clinicians compared with active cancer therapy (very low certainty).

1 finding from 1 review

Active cancer therapy combined with TCM vs active cancer therapy

Adverse events ‐ renal and hepatic impairment ‐ Fuzheng Guben granules · patients with oesophageal cancer

Active cancer therapy combined with TCM may leads to lower adverse events ‐ renal and hepatic impairment ‐ Fuzheng Guben granules compared with active cancer therapy (low certainty).

1 finding from 1 review

Sublingual immunotherapy vs control

All adverse events Weighted mean duration of studies: 60 weeks** · people with asthma

Sublingual immunotherapy leads to higher all adverse events Weighted mean duration of studies: 62 weeks** compared with control (high certainty).

1 finding from 1 review

Split‐course radiotherapy (8 fractions, 30 Gy) vs short‐course radiotherapy (16 Gy

Adverse events Grade 3 oesophagitis, diarrhoea and nausea · adults with metastatic extradural spinal cord compression (poor prognosis, no spinal instability or bony impingement of cord)

Split‐course radiotherapy (8 fractions, 30 Gy) showed no clear difference in adverse events Grade 3 oesophagitis, diarrhoea, and nausea compared with short‐course radiotherapy (2 fractions, 16 Gy) (moderate certainty).

1 finding from 1 review

Sublingual immunotherapy vs control

Serious adverse events Weighted mean duration of studies: 49 weeks · people with asthma

Sublingual immunotherapy showed no clear difference in serious adverse events Weighted mean duration of studies: 56 weeks compared with control (moderate certainty).

1 finding from 1 review