Cochrane · systematic review · CD013170

Cough augmentation techniques for people with chronic neuromuscular disorders

Morrow, B, Argent, A, Zampoli, M, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

NeuromuscularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
3
No studies
9
Included studies
NR
No studies 9 · 75%Ungraded 0 · 0%Very low 3 · 25%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Cough augmentation therapy compared with an alternative cough augmentation technique or combination of techniques for people with neuromuscular diseases

Population: participants with chronic neuromuscular diseases
6 questions
OutcomeEffectEvidenceStatus / GRADE
Number of unscheduled hospital admissions for 'maintenance therapy'
Cough augmentation therapy vs an alternative cough augmentation technique or combination of techniques
no estimate extractedNRNo studies
Duration of hospital stay (days) for 'rescue' therapy
Cough augmentation therapy vs an alternative cough augmentation technique or combination of techniques
no estimate extractedNRNo studies
PCF
Cough augmentation therapy vs an alternative cough augmentation technique or combination of techniques
no estimate extracted8 studies · 198 participantsVery low
Downgraded: risk of bias, imprecision
Any adverse events
Cough augmentation therapy vs an alternative cough augmentation technique or combination of techniques
no estimate extracted64 participantsVery low
Downgraded: risk of bias, imprecision
Quality of life for 'maintenance' therapy
Cough augmentation therapy vs an alternative cough augmentation technique or combination of techniques
no estimate extractedNRNo studies
Participant preference or satisfaction for 'rescue' and 'maintenance' therapy
Cough augmentation therapy vs an alternative cough augmentation technique or combination of techniques
no estimate extractedNRNo studies

Cough augmentation therapy compared with standard care for people with neuromuscular diseases

Population: participants with chronic neuromuscular diseases
6 questions
OutcomeEffectEvidenceStatus / GRADE
Number of unscheduled hospital admissions for 'maintenance' therapy
Cough augmentation therapy vs standard care
no estimate extractedNRNo studies
Duration of hospital stay (days) for 'rescue' therapy
Cough augmentation therapy vs standard care
no estimate extractedNRNo studies
Quality of life for 'maintenance' therapy
Cough augmentation therapy vs standard care
no estimate extractedNRNo studies
Peak cough flow for 'rescue' or 'maintenance' therapy
Cough augmentation therapy vs standard care
no estimate extractedNRNo studies
Any adverse events for 'rescue' and 'maintenance' therapy
Cough augmentation therapy vs standard care
no estimate extracted1 study · 67 participantsVery low
Downgraded: risk of bias, imprecision
Participant preference or satisfaction for 'rescue' or 'maintenance' therapy
Cough augmentation therapy vs standard care
no estimate extractedNRNo studies